EMT-related gene Slug in ovarian cancer

HOXC10 promotes tumour metastasis by regulating the EMT-related gene Slug in ovarian cancer

metastatic symptoms. Recent studies have shown that HOX genes are crucial in tumour progression, but the underlying mechanisms remain unclear. Here, HOXC10 expression was examined in ovarian cancer tissues. The function of HOXC10 in ovarian cancer metastasis was investigated in vitroand via intraperitoneal injection in vivo. A total of 158 ovarian cancer patients with adequate records were enrolled for analysis. HOXC10 was associated with metastasis and poor prognosis in ovarian cancer. In vitro, HOXC10 overexpression promoted ovarian cancer cell migration.

Moreover, HOXC10 positively regulated Slug expression, altering the migration ability of cancer cells. Furthermore, our study showed that miR-222-3p was a suppressor of HOXC10. In vivo, a decrease in hepatic metastasis was seen in xenograft mice harbouring tumours with stable HOXC10 overexpression after miR-222-3p agomir (an overexpression reagent) injection. This study provides the first evidence that HOXC10 promotes ovarian cancer metastasis by regulating the transcription of the EMT-related gene Slug. Moreover, we found that HOXC10 is regulated by miR-222-3p. These data highlight the crucial role of HOXC10 in enhancing ovarian cancer metastasis and may provide a therapeutic target for ovarian cancer.

Cancer Antigen 125 Antigen (Ascites Fluid)

VAng-Cr3870-10kU 10 kU
EUR 1132.8
Description: Cancer Antigen 125 Antigen, Host/Source: Ascites Fluid. The purity is ≥ 95% by SDS-PAGE.

Cancer Antigen 125 Antigen (Human Adenocarcinoma)

VAng-Cr3868-10kU 10 kU
EUR 505.2
Description: Cancer Antigen 125 Antigen, Host/Source: Human Adenocarcinoma. The purity is detected by salt extraction and chromatography.

Human carcinoembryonic antigen (CEA) antigen

CEA15-N-100 100 ug
EUR 270

Cancer Antigen CEA Antigen (Human Fluids)

VAng-Wyb8644-inquire inquire Ask for price
Description: Carcinoembryonic Antigen, Calibrator Grade, Cancer antigen from Human Fluids, 1.13 mg/mL.

Cancer Antigen 19-9 Antigen (Liver Carcinoma)

VAng-Cr3873-10kU 10 kU
EUR 472.8
Description: Cancer Antigen 19-9 Antigen, Host/Source: Liver Carcinoma. The purity is detected by gel filtration and ion-exchange chromatography. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Prostate Specific Antigen Std Grade Antigen

VAng-Cr3891-1mg 1 mg
EUR 604.8
Description: Prostate Specific Antigen Std Grade Antigen, Host/Source: Human Seminal Fluid. The purity is detected by salt precipitation.

Cancer Antigen 125 Antigen (Human Adenocarcinoma) (> 90%)

VAng-Cr3869-25kU 25 kU
EUR 967.2
Description: Cancer Antigen 125 Antigen, Host/Source: Human Adenocarcinoma. The purity is> 90% by SDS-PAGE. Matched Pair: HM183, HM184, HM185, HM186.

HBV surface recombinant antigen HBsAg antigen

00123-V-01mg 0,1 mg
EUR 321
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity

HBV surface recombinant antigen HBsAg antigen

00123-V-1000ug 1000 ug
EUR 1539
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity

HBV surface recombinant antigen HBsAg antigen

00124-V-01mg 0,1 mg
EUR 321
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant

HBV surface recombinant antigen HBsAg antigen

00124-V-1000ug 1000 ug
EUR 1539
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant

Cancer Antigen 19-9 Antigen (Liver Carcinoma) (> 90%)

VAng-Cr3875-25kU 25 kU
EUR 885.6
Description: Cancer Antigen 19-9 Antigen, Host/Source: Liver Carcinoma. The purity is> 90% by SDS-PAGE. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Cancer Antigen AFP Antigen (Human Cord Blood)

VAng-Wyb8624-inquire inquire Ask for price
Description: Alpha Fetoprotein (66 kDa), Cancer antigen from Human Cord Blood, 1.73 mg/mL.

Cancer Antigen CA-125 Antigen (Human Fluids)

VAng-Wyb8639-inquire inquire Ask for price
Description: CA-125, Calibrator Grade, cancer antigen from Human Fluids, 53.26 KU/mL.

Cancer Antigen 15-3 MUC 1 Antigen (Human Milk)

VAng-Cr3871-10kU 10 kU
EUR 505.2
Description: Cancer Antigen 15-3 MUC 1 Antigen, Host/Source: Human Milk. The purity is detected by salt extraction and delipidization following high speed centrifugation. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

MPO Antigen

E61A00501 1mg
EUR 1230

HAV Antigen

E61H00101 1mg
EUR 733.2

HBS Antigen

E61H00301 1mg
EUR 374.4

HBS Antigen

E61H00302 1mg
EUR 374.4

HBe Antigen

E61H00501 1mg
EUR 463.2

HBc Antigen

E61H00701 1mg
EUR 463.2

AFP Antigen

E62C002 20ug
EUR 458.4

HCG Antigen

E62C004 100ug
EUR 458.4

CEA Antigen

E62C010 20ug
EUR 458.4

CK8 Antigen

E62C02001 20ug
EUR 458.4

CRP Antigen

E64C00501 1mg
EUR 840

CRP Antigen

E64C00502 1mg
EUR 840

CD9 Antigen

E6TA00101 0.1mg
EUR 411.6

BSA Antigen

IM112 1 ml
EUR 342
Description: BSA Antigen by Cygnus Technologies is available in Europe via Gentaur.

HSA Antigen

IM118 1 ml
EUR 342
Description: HSA Antigen by Cygnus Technologies is available in Europe via Gentaur.

CDV Antigen

VAng-Lsx0016-1mg 1 mg
EUR 1688.4
Description: Canine Distemper Virus Antigen from SL-29 cells.

Gastrointestinal Cancer Antigen (CA 19-9), antigen grade

CA1991-N-10 10 KU
EUR 634.8

S100 Antigen

E62B003 20ug
EUR 458.4

CA50 Antigen

E62C009 10KU
EUR 458.4

CK18 Antigen

E62C02101 20ug
EUR 458.4

CK20 Antigen

E62C02201 20ug
EUR 458.4

GP73 antigen

E62C02701 20ug
EUR 458.4

TP17 Antigen

E62H00701 100ug
EUR 458.4

TP47 Antigen

E62H00702 100ug
EUR 458.4

cTnI antigen

E64C00101 100ug
EUR 508.8

cTnI antigen

E64C00102 100ug
EUR 733.2

cTnC antigen

E64C01301a 20ug
EUR 411.6

sST2 antigen

E64C01501 20ug
EUR 411.6

PAPP Antigen

E64D00101 100ug
EUR 1425.6

PAPP Antigen

E64D00102 1mg
EUR 5910

CD63 Antigen

E6TA00102 0.1mg
EUR 411.6

CD81 Antigen

E6TA00103 0.1mg
EUR 411.6

Cancer Antigen CEA Antigen (Human Metastatic Liver)

VAng-Wyb8645-inquire inquire Ask for price
Description: Carcinoembryonic Antigen, Antigen Grade, Cancer antigen from Human Metastatic Liver, 5.5 mg/mL.

CA242 Antigen

E62C00601 50KU
EUR 2078.4

CA242 Antigen

E62C00602 10KU
EUR 458.4

CA199 Antigen

E62C007 10KU
EUR 458.4

CA199 Antigen

E62C00701 50KU
EUR 1180.8

CA199 Antigen

E62C00702 50KU
EUR 1620

CA125 Antigen

E62C011 10KU
EUR 458.4

CA153 Antigen

E62C012 10KU
EUR 458.4

EpCAM Antigen

E64B00107 0.1mg
EUR 411.6

HSP70 Antigen

E6TA00104 0.1mg
EUR 411.6

CD133 Antigen

E6TA00105 0.1mg
EUR 411.6

CD32a Antigen

E6TA00106 0.1mg
EUR 411.6

Cancer Antigen CA-125 Antigen (Human Adenocarcinoma)

VAng-Wyb8642-inquire inquire Ask for price
Description: CA-125, Calibrator Grade, Cancer antigen from Human Adenocarcinoma, 500 kIU / mL.

S100BB Antigen

E62B00201 20ug
EUR 458.4

S100BB Antigen

E62B00202 20ug
EUR 458.4

Giardia Trophozoite Recombinant antigen antigen 34 kDa

00321-V-01mg 0,1 mg
EUR 321
Description: Giardia Trophozoite Recombinant antigen antigen 34 kDa a.a. 21-280

Giardia Trophozoite Recombinant antigen antigen 34 kDa

00321-V-1000ug 1000 ug
EUR 1539
Description: Giardia Trophozoite Recombinant antigen antigen 34 kDa a.a. 21-280

Cancer Antigen 19-9 Antigen (Liver Carcinoma) (High purity)

VAng-Cr3874-25kU 25 kU
EUR 1033.2
Description: Cancer Antigen 19-9 Antigen, Host/Source: Liver Carcinoma.

S100A1B Antigen

E62B00101 20ug
EUR 458.4

S100A1B Antigen

E62B00102 20ug
EUR 458.4

Insulin Antigen

E64I001 1mg
EUR 418.8

Insulin Antigen

IM121 1 ml
EUR 342
Description: Insulin Antigen by Cygnus Technologies is available in Europe via Gentaur.

Ferritin Antigen

E62C013 100ug
EUR 458.4

Ferritin Antigen

E62C01304 100ug
EUR 458.4

Copeptin antigen

E64C01601 100ug
EUR 411.6

Cancer Antigen AFP Antigen (Human hepatocellular carcinoma)

VAng-Wyb8625-inquire inquire Ask for price
Description: Alpha Fetoprotein, Antigen Grade, Cancer antigen from human hepatocellular carcinoma, 2.93 mg/mL.

Rotavirus Antigen

DAGA-258 1 ml dry ice
EUR 873.6

Cancer Antigen 15-3 MUC 1 Antigen (Human Ascites Fluid)

VAng-Cr3872-10kU 10 kU
EUR 1363.2
Description: Cancer Antigen 15-3 MUC 1 Antigen, Host/Source: Human Ascites Fluid.

Enterovirus Antigen

30-1984 1 mg
EUR 855.6
Description: Enterovirus Protein

Hydrocodone Antigen

VAng-Cr3693-1mg 1 mg
EUR 967.2
Description: Hydrocodone Antigen, matched pairs: JP101, JP102 or JP103 (detection); Used for ELISA, Lateral Flow.

RV Antigen (E1)

E61Y00101 1mg
EUR 840

Calprotectin Antigen

DAG-T1230 1mg
EUR 4446

SS-A Antigen

E61A00301 1mg
EUR 1230

SS-B Antigen

E61A00401 1mg
EUR 1230

IL-2 antigen

E6IE600106 20ug
EUR 411.6

IL-4 antigen

E6IE600107 20ug
EUR 411.6

IL-6 antigen

E6IE600108 20ug
EUR 411.6

IL-2 antigen

E6L00106 20ug
EUR 458.4

IL-4 antigen

E6L00107 20ug
EUR 458.4

IL-6 antigen

E6L00108 20ug
EUR 458.4

Thyroglobulin Antigen

VAng-Cr3893-1mg 1 mg
EUR 604.8
Description: Thyroglobulin Antigen, Host/Source: Human Thyroid Tissue. The purity is> 95% by SDS-PAGE.

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCA0228-250 250uL
EUR 459.6
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),APC conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC800228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF680 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC800228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF680 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC810228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF680R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC810228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF680R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC940228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF594 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC940228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF594 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC700228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF770 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC700228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF770 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC880228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF488A conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC880228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF488A conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC430228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF543 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC430228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF543 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC400228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF640R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC400228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF640R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC050228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF405M conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC050228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF405M conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCB0228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),Biotin conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCB0228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),Biotin conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCAP0228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCAP0228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCR0228-250 250uL
EUR 459.6
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),RPE conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCP0228-250 250uL
EUR 459.6
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),PerCP conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNUM0228-50 50uL
EUR 474
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6), 1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCH0228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCH0228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNUB0228-100 100uL
EUR 250.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6), Concentration: 0.2mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNUB0228-500 500uL
EUR 549.6
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6), Concentration: 0.2mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC040228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF405S conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC040228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF405S conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC550228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF555 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC550228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF555 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC610228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF660R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC610228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF660R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC680228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF568 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC680228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF568 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC470228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF647 conjugate, Concentration: 0.1mg/mL

Comparison between Single- and Group-housed Pregnant Sows for Direct and Indirect Physiological, Reproductive, Welfare Indicators and Gene Expression Profiling

 Single- and group-housed pregnant sows were assessed during 8 weeks (4th and 8th to 14th) with regard to physiological, reproductive, welfare indicators and gene expression profiling. Compared to single-housed sows, group-housed sows had decreased non-return to estrus at 56 days after artificial insemination (AI) (83% vs 92%) and farrowing rate (78% vs 88%), respectively. Furthermore, group-housed sows showed a higher degree (p < 0.01) of advantageous physiological indicators, such as albumin (odds ratio [OR] = 4.4), alkaline phosphatase (OR = 1.5), bactericidal (OR = 3.2) and complement (OR = 24.3), and disadvantageous for alanine amino transferase (OR = 0.5), bilirubin (OR = 0.4), lysozyme (OR = 0.3) and C-reactive protein compared to single-housed.

Eighty-seven genes related to immune response were underexpressed (log fold change ≤ 1.5; p < 0.05) during the 8th to 14th weeks in the group compared to single-housed sows, which in turn showed an immunomodulatory reduction on the expression of 43 genes during the 11th to 14th compared to the 4th week. Overall, the results were interpreted as indicative of greater comfort state of the group compared to single-housed sows.

Syndecan-1 and KRAS Gene Expression Signature Associates With Patient Survival in Pancreatic Cancer

  •  Objectives: The purpose of this study was to investigate the association of syndecan-1 (SDC1) and KRAS molecular characteristics with patient survival in pancreatic cancer.
  • Methods: Both SDC1 mRNA and methylation and KRAS mRNA and somatic mutations, as well as clinical data were retrieved from a The Cancer Genome Alta pancreatic cancer data set for survival analyses. Kyoto Encyclopedia of Gene and Genomes pathway analysis for coexpressed genes for either SDC1 or KRAS was performed, respectively.
  • Results: A significantly negative correlation existed between SDC1 mRNA and DNA methylation. Patients with KRAS somatic mutations had a significantly higher SDC1 mRNA but lower methylation than those without the mutations. Compared with patients with KRASSDC1 signature, those with a high level of KRAS and SDC1 alone or both had a significantly elevated mortality. The adjusted hazard ratios (95% confidence interval) were 2.30 (1.16-4.54, P = 0.017) for KRASSDC1, 2.85 (1.48-5.49, P = 0.002) for KRASSDC1, and 2.48 (1.31-4.70, P = 0.005) for KRASSDC1, respectively. Several Kyoto Encyclopedia of Gene and Genomes pathways were shared, whereas there were distinct pathways between KRAS and SDC1 coexpressed genes.
  • Conclusions: SDC1 interplays with KRAS, and targeting both KRAS and SDC1 in combination may be more beneficial to pancreatic cancer patients.

Short communication: Genome-wide identification of new reference genes for reverse-transcription quantitative PCR in Streptococcus thermophilus based on RNA-sequencing analysis

 Streptococcus thermophilus, one of the most important industrial lactic acid bacteria, is widely used for the production of fermented dairy products such as yogurt and cheese. The accuracy of gene expression-based analyses (e.g., reverse-transcription quantitative real-time PCR) relies heavily on the selection of reliable reference genes (RG), which provides the basis for correctly interpreting expression data. However, many traditional RG are not stably expressed in different systems. Here we used RNA-sequencing to systematically investigate gene expression variation at the genome scale and identify more stable RG in S. thermophilus.

In total, 21 putative candidate RG were identified with variation coefficient values <10.0 based on the expression of all 1,911 genes under 4 different experimental conditions. We selected and validated 12 RG chosen from transcriptomes by using reverse-transcription quantitative real-time PCR, and ranked their expression stability by statistical algorithms geNorm and NormFinder. Compared with traditional RG 16S rRNA, genes encoding glycine-tRNA ligase subunit β GlyS and fatty acid-binding protein DegV were more stable under all 4 treatments, which have never been used as RG in S. thermophilus. Our finding provides the foundation for more precise analysis of gene expression in S. thermophilus and other lactic acid bacteria species.

PLDN antibody

70R-19338 50 ul
EUR 522
Description: Rabbit polyclonal PLDN antibody

PLDN antibody

70R-35798 100 ug
EUR 418.8
Description: Rabbit polyclonal PLDN antibody

PLDN Antibody

DF12041 200ul
EUR 420

anti- PLDN antibody

FNab06531 100µg
EUR 606.3
Description: Antibody raised against PLDN

Pallidin Homolog (PLDN) Antibody

20-abx114318
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Polyclonal PLDN antibody - middle region

AMM07239G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PLDN - middle region. This antibody is tested and proven to work in the following applications:

Biogenesis of Lysosomal Organelles Complex 1 Subunit 6 (PLDN) Antibody

abx236531-100ug 100 ug
EUR 577.2

Biogenesis of Lysosomal Organelles Complex 1 Subunit 6 (PLDN) Antibody

abx036189-100ug 100 ug
EUR 469.2

PLDN cloning plasmid

CSB-CL890745HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the PLDN gene.

PLDN Blocking Peptide

33R-2437 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PLDN antibody, catalog no. 70R-2858

PLDN Blocking Peptide

33R-6524 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PLDN antibody, catalog no. 70R-2857

PLDN Blocking Peptide

DF12041-BP 1mg
EUR 234

PLDN protein (His tag)

80R-2215 50 ug
EUR 386.4
Description: Purified recombinant Human PLDN Protein (His tag)

PLDN ELISA KIT|Human

EF001846 96 Tests
EUR 826.8

PLDN Recombinant Protein (Rat)

RP220886 100 ug Ask for price

PLDN Recombinant Protein (Mouse)

RP162719 100 ug Ask for price

PLDN Recombinant Protein (Human)

RP023749 100 ug Ask for price

Pldn ORF Vector (Rat) (pORF)

ORF073630 1.0 ug DNA
EUR 607.2

PLDN ORF Vector (Human) (pORF)

ORF007917 1.0 ug DNA
EUR 114

Pldn ORF Vector (Mouse) (pORF)

ORF054241 1.0 ug DNA
EUR 607.2

Rat Pallidin(PLDN)ELISA kit

QY-E10560 96T
EUR 433.2

Human Pallidin (PLDN)ELISA kit

201-12-2524 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Mouse Pallidin, Pldn ELISA KIT

ELI-36376m 96 Tests
EUR 1038

Human Pallidin, PLDN ELISA KIT

ELI-21687h 96 Tests
EUR 988.8

Mouse Pallidin(PLDN)ELISA kit

QY-E21136 96T
EUR 433.2

Human Pallidin(PLDN)ELISA Kit

QY-E04062 96T
EUR 433.2

Human Pallidin (PLDN)ELISA kit

YLA3193HU-48T 48T
EUR 435

Human Pallidin (PLDN)ELISA kit

YLA3193HU-96T 96T
EUR 562.5

Pldn sgRNA CRISPR Lentivector set (Rat)

K7200301 3 x 1.0 ug
EUR 406.8

Anti-PLDN antibody

PAab06531 100 ug
EUR 426

Pldn 3'UTR GFP Stable Cell Line

TU166520 1.0 ml Ask for price

PLDN 3'UTR GFP Stable Cell Line

TU068229 1.0 ml
EUR 2799.6

Pldn 3'UTR GFP Stable Cell Line

TU266380 1.0 ml Ask for price

PLDN sgRNA CRISPR Lentivector set (Human)

K1664801 3 x 1.0 ug
EUR 406.8

Pldn sgRNA CRISPR Lentivector set (Mouse)

K3722301 3 x 1.0 ug
EUR 406.8

PLDN Protein Vector (Rat) (pPM-C-HA)

PV294520 500 ng
EUR 723.6

PLDN Protein Vector (Rat) (pPB-C-His)

PV294518 500 ng
EUR 723.6

PLDN Protein Vector (Rat) (pPB-N-His)

PV294519 500 ng
EUR 723.6

PLDN Protein Vector (Rat) (pPM-C-His)

PV294521 500 ng
EUR 723.6

PLDN Protein Vector (Human) (pPM-C-HA)

PV031667 500 ng
EUR 394.8

PLDN Protein Vector (Mouse) (pPM-C-HA)

PV216964 500 ng
EUR 723.6

PLDN Protein Vector (Human) (pPB-C-His)

PV031665 500 ng
EUR 394.8

PLDN Protein Vector (Human) (pPB-N-His)

PV031666 500 ng
EUR 394.8

PLDN Protein Vector (Human) (pPM-C-His)

PV031668 500 ng
EUR 394.8

PLDN Protein Vector (Mouse) (pPB-C-His)

PV216962 500 ng
EUR 723.6

PLDN Protein Vector (Mouse) (pPB-N-His)

PV216963 500 ng
EUR 723.6

PLDN Protein Vector (Mouse) (pPM-C-His)

PV216965 500 ng
EUR 723.6

Pldn 3'UTR Luciferase Stable Cell Line

TU116520 1.0 ml Ask for price

PLDN 3'UTR Luciferase Stable Cell Line

TU018229 1.0 ml
EUR 2799.6

Pldn 3'UTR Luciferase Stable Cell Line

TU216380 1.0 ml Ask for price

PLDN Pallidin Homolog Human Recombinant Protein

PROTQ9UL45 Regular: 10ug
EUR 380.4
Description: PLDN Human Recombinant produced in E. coli is a single polypeptide chain containing 192 amino acids (1-172) and having a molecular mass of 21.9kDa.;PLDN is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Pldn sgRNA CRISPR Lentivector (Rat) (Target 1)

K7200302 1.0 ug DNA
EUR 184.8

Pldn sgRNA CRISPR Lentivector (Rat) (Target 2)

K7200303 1.0 ug DNA
EUR 184.8

Pldn sgRNA CRISPR Lentivector (Rat) (Target 3)

K7200304 1.0 ug DNA
EUR 184.8

PLDN sgRNA CRISPR Lentivector (Human) (Target 1)

K1664802 1.0 ug DNA
EUR 184.8

PLDN sgRNA CRISPR Lentivector (Human) (Target 2)

K1664803 1.0 ug DNA
EUR 184.8

PLDN sgRNA CRISPR Lentivector (Human) (Target 3)

K1664804 1.0 ug DNA
EUR 184.8

Pldn sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3722302 1.0 ug DNA
EUR 184.8

Pldn sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3722303 1.0 ug DNA
EUR 184.8

Pldn sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3722304 1.0 ug DNA
EUR 184.8

Recombinant Human PLDN Protein, His, E.coli-1mg

QP13077-1mg 1mg
EUR 6301.2

Recombinant Human PLDN Protein, His, E.coli-2ug

QP13077-2ug 2ug
EUR 186

Recombinant Human PLDN Protein, His, E.coli-10ug

QP13077-10ug 10ug
EUR 241.2

PLDN Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV629023 1.0 ug DNA
EUR 616.8

PLDN Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV629027 1.0 ug DNA
EUR 616.8

PLDN Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV629028 1.0 ug DNA
EUR 616.8

Pldn sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K7200305 3 x 1.0 ug
EUR 451.2

PLDN sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K1664805 3 x 1.0 ug
EUR 451.2

Pldn sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3722305 3 x 1.0 ug
EUR 451.2

Pldn sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K7200306 1.0 ug DNA
EUR 200.4

Pldn sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K7200307 1.0 ug DNA
EUR 200.4

Pldn sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K7200308 1.0 ug DNA
EUR 200.4

PLDN sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K1664806 1.0 ug DNA
EUR 200.4

PLDN sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K1664807 1.0 ug DNA
EUR 200.4

PLDN sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K1664808 1.0 ug DNA
EUR 200.4

Pldn sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3722306 1.0 ug DNA
EUR 200.4

Pldn sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3722307 1.0 ug DNA
EUR 200.4

Pldn sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3722308 1.0 ug DNA
EUR 200.4

PLDN Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV629024 1.0 ug DNA
EUR 616.8

PLDN Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV629025 1.0 ug DNA
EUR 686.4

PLDN Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV629026 1.0 ug DNA
EUR 686.4

PLD2 Antibody

AF7603 200ul
EUR 540

PLD1 Antibody

AF7871 200ul
EUR 540

PLD3 Antibody

39791-100ul 100ul
EUR 468

PLD1 Antibody

AF4765 200ul
EUR 540

PLD2 Antibody

AF6974 100ul
EUR 420

PLD3 antibody

70R-6831 50 ug
EUR 560.4
Description: Rabbit polyclonal PLD3 antibody raised against the N terminal of PLD3

PLD2 antibody

70R-7964 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal PLD2 antibody

PLD2 antibody

70R-8244 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal PLD2 antibody

PLD1 antibody

70R-31530 100 ug
EUR 392.4
Description: Rabbit polyclonal PLD1 antibody

PLD1 antibody

70R-19337 50 ul
EUR 522
Description: Rabbit polyclonal PLD1 antibody

PLD3 antibody

70R-36350 100 ug
EUR 418.8
Description: Rabbit polyclonal PLD3 antibody

PLD4 antibody

70R-35616 100 ug
EUR 418.8
Description: Rabbit polyclonal PLD4 antibody

PLD4 Antibody

34905-100ul 100ul
EUR 302.4

PLD4 Antibody

34905-50ul 50ul
EUR 224.4

PLD2 Antibody

46133-100ul 100ul
EUR 302.4

PLD2 Antibody

46133-50ul 50ul
EUR 224.4

PLD1 Antibody

45148-100ul 100ul
EUR 302.4

PLD1 Antibody

45148-50ul 50ul
EUR 224.4

PLD1 Antibody

ABD13213 100 ug
EUR 525.6

PLD3 Antibody

ABD13214 100 ug
EUR 525.6

PLD4 Antibody

ABD4294 100 ug
EUR 525.6

PLD1 Antibody

ABD7802 100 ug
EUR 525.6

PLD2 Antibody

ABD9752 100 ug
EUR 525.6

PLD3 Antibody

ABD9753 100 ug
EUR 525.6

PLD2 Antibody

DF9752 200ul
EUR 420

PLD3 Antibody

DF9753 200ul
EUR 420

PLD1 Antibody

DF7802 200ul
EUR 420

PLD4 Antibody

DF4294 200ul
EUR 420

PLD4 Antibody

CSB-PA219574- each
EUR 402
Description: A polyclonal antibody against PLD4. Recognizes PLD4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

PLD4 Antibody

CSB-PA219574-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against PLD4. Recognizes PLD4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

PLD6 Antibody

1-CSB-PA836649LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD6. Recognizes PLD6 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200

PLD5 Antibody

1-CSB-PA836686LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD5. Recognizes PLD5 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

PLD4 Antibody

1-CSB-PA839298LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD4. Recognizes PLD4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200

PLD3 Antibody

1-CSB-PA008426
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD3. Recognizes PLD3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/5000

PLD1 Antibody

1-CSB-PA030081
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD1. Recognizes PLD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/5000

PLD1 Antibody

1-CSB-PA030082
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD1. Recognizes PLD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

PLD2 Antibody

1-CSB-PA030084
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD2. Recognizes PLD2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

PLD1 Antibody

1-CSB-PA018144GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against PLD1. Recognizes PLD1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

PLD2 Antibody

1-CSB-PA018145LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD2. Recognizes PLD2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

PLD3 Antibody

1-CSB-PA018146LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD3. Recognizes PLD3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

PLD1 Antibody

1-CSB-PA614406LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD1. Recognizes PLD1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

PLD4 Antibody

1-CSB-PA006980
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PLD4. Recognizes PLD4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

PLD2 antibody

PAab10085 100 ug
EUR 463.2

PLD1 Antibody

R30165 100 ug
EUR 356.15
Description: This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties.

PLD1 Antibody

R32213 100 ug
EUR 356.15
Description: By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.

anti- PLD2 antibody

FNab10085 100µg
EUR 658.5
Description: Antibody raised against PLD2

anti- PLD1 antibody

FNab06530 100µg
EUR 606.3
Description: Antibody raised against PLD1

PLD2 (pY169) Antibody

abx333307-100ul 100 ul
EUR 560.4

PLD1 (pT147) Antibody

abx333429-100ul 100 ul
EUR 560.4

PLD1 antibody (Ser561)

70R-31529 100 ug
EUR 392.4
Description: Rabbit polyclonal PLD1 antibody (Ser561)