Berberine Inhibits the gene Expression and Production

Berberine Inhibits the gene Expression and Production of Proinflammatory Cytokines by Mononuclear cells in Rheumatoid Arthritis and Healthy Individuals

•  Objective: Rheumatoid arthritis (RA) is the most prevalent autoimmune arthritis. Berberine is an alkaloid isolated from Berberis vulgaris and its anti-inflammatory effect has been identified.
• Method: Twenty newly diagnosed RA patients and 20 healthy controls participated. Peripheral mononuclear cells were prepared and stimulated with bacterial lipopolysachharide (LPS,1 µg/ml), exposed to different concentrations of berberine (10 and 50µM) and dexamethasone (10-7 M) as a reference. Toxicity of compounds was evaluated by WST-1 assay. Expression of TNF-α and IL-1β were determined by quantitative real-time PCR. Protein level of secreted TNF-α and IL1β were measured by using ELISA.
• Result: Berberine did not have any toxic effect on cells, whereas Lipopolysachharide (LPS) stimulation caused a noticeable rise in TNF-α and IL-1β production. Berberine markedly downregulated the expression of both TNF-α and IL1β and inhibits TNF-α and IL-1β secretion from LPS-stimulated PBMCs.
• Discussion: This study provided molecular basis for anti-inflammatory effect of berberine on human mononuclear cells through the suppression of TNF-a and IL-1secretion. Our findings highlighted the significant inhibitory effect of berberine on proinflammatory responses of mononuclear cells from rheumatoid arthritis individuals, which may be responsible for antiinflammatory property of Barberry. We observed that berberine at high concentration exhibited anti-inflammatory effect in PBMCs of both healthy and patient groups by suppression of TNF-a and IL-1cytokines at both mRNA and protein levels.
• Conclusions: Berberine may inhibit the gene expression and production of pro-inflammatory cytokines by mononuclear cells in rheumatoid arthritis and healthy individuals without affecting cells viability. Future studies with larger sample size is needed to prove the idea.

Parainfluenza Type-2 Protein
30-1996	Fitzgerald	50 ug	EUR 280.8
Description: Purified Parainfluenza type 2 protein

Parainfluenza type 2 antibody (FITC)
61C-CR3015M1F	Fitzgerald	100 ug	EUR 553.2
Description: Mouse monoclonal Parainfluenza type 2 antibody (FITC)

Parainfluenza type 2 protein
30-AP53	Fitzgerald	1 ml	EUR 489.6
Description: Purified Parainfluenza type 2 protein

Parainfluenza Virus, Canine Antigen
DAGA-513	Creative Diagnostics	1mg	EUR 1263.6

Parainfluenza Type 2&3 Antibody (HRP)
abx023112-1ml	Abbexa	1 ml	EUR 718.8

Parainfluenza type 1 antibody
10-P43A	Fitzgerald	1 mg	EUR 609.6
Description: Mouse monoclonal Parainfluenza type 1 antibody

Parainfluenza type 1 antibody
10-P43B	Fitzgerald	1 mg	EUR 588
Description: Mouse monoclonal Parainfluenza type 1 antibody

Parainfluenza type 1 antibody
10-P43D	Fitzgerald	1 mg	EUR 159.6
Description: Mouse monoclonal Parainfluenza type 1 antibody

Parainfluenza type 3 antibody
10-P63A	Fitzgerald	1 mg	EUR 537.6
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 3 antibody
10-P63B	Fitzgerald	1 mg	EUR 537.6
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 3 antibody
10-P63C	Fitzgerald	1 mg	EUR 418.8
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 3 antibody
10C-CR3016M1	Fitzgerald	100 ug	EUR 489.6
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 3 antibody
10C-CR3016M2	Fitzgerald	100 ug	EUR 163.2
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 3 antibody
10C-CR3016M3	Fitzgerald	100 ug	EUR 163.2
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 1 antibody
20-PG89	Fitzgerald	1 mg	EUR 139.2
Description: Goat polyclonal Parainfluenza type 1 antibody

Parainfluenza Type 1 Antibody
abx022123-1mg	Abbexa	1 mg	EUR 994.8

Parainfluenza Type 3 Antibody
abx022126-1mg	Abbexa	1 mg	EUR 994.8

Parainfluenza Type 3 Antibody
abx022127-1mg	Abbexa	1 mg	EUR 994.8

Parainfluenza Type 1 Antibody
abx022128-1mg	Abbexa	1 mg	EUR 777.6

Parainfluenza Type 3 Antibody
abx022130-1mg	Abbexa	1 mg	EUR 777.6

Parainfluenza Virus Type-2
7-07954	CHI Scientific	10µg	Ask for price

Parainfluenza Virus Type-2
7-07955	CHI Scientific	50µg	Ask for price

Parainfluenza Virus Type-2
7-07956	CHI Scientific	1mg	Ask for price

Parainfluenza type 1 + 3 antibody
10-P43C	Fitzgerald	1 mg	EUR 523.2
Description: Mouse monoclonal Parainfluenza type 1 + 3 antibody

Parainfluenza Type 1&3 Antibody
abx022122-1mg	Abbexa	1 mg	EUR 994.8

Parainfluenza type 3 antibody (FITC)
61C-CR3016M2F	Fitzgerald	100 ug	EUR 553.2
Description: Mouse monoclonal Parainfluenza type 3 antibody (FITC)

Parainfluenza Type-1 protein
30-1995	Fitzgerald	50 ug	EUR 295.2
Description: Purified Parainfluenza type 1 protein

Parainfluenza Type-3 Protein
30-1997	Fitzgerald	50 ug	EUR 295.2
Description: Purified Parainfluenza type 3 protein

Parainfluenza type 1 protein
30-AP43	Fitzgerald	1 ml	EUR 508.8
Description: Purified Parainfluenza type 1 protein

Parainfluenza type 3 protein
30-AP63	Fitzgerald	1 ml	EUR 489.6
Description: Purified Parainfluenza type 3 protein

Parainfluenza Virus Type-2 Protein
20-abx260514	Abbexa	EUR 276.00 EUR 3082.80 EUR 393.60	10 ug 1 mg 50 ug

Parainfluenza Virus Type-1
7-07951	CHI Scientific	10µg	Ask for price

Parainfluenza Virus Type-1
7-07952	CHI Scientific	50µg	Ask for price

Parainfluenza Virus Type-1
7-07953	CHI Scientific	1mg	Ask for price

Parainfluenza Virus Type-3
7-07957	CHI Scientific	10µg	Ask for price

Parainfluenza Virus Type-3
7-07958	CHI Scientific	50µg	Ask for price

Parainfluenza Virus Type-3
7-07959	CHI Scientific	1mg	Ask for price

Monoclonal Anti-Sendai virus/Parainfluenza type 3 (SeV/Parainfluenza virus 3) IgG
SEND31-M	Alpha Diagnostics	100 ug	EUR 578.4

Mouse antibody for Parainfluenza virus type 2
1241	Virostat	100 ug	EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 2 for WB, ELISA.

Parainfluenza Virus Type-1 Protein
20-abx260513	Abbexa	EUR 276.00 EUR 3082.80 EUR 393.60	10 ug 1 mg 50 ug

Parainfluenza Virus Type-3 Protein
20-abx260515	Abbexa	EUR 276.00 EUR 3082.80 EUR 393.60	10 ug 1 mg 50 ug

Monoclonal Anti-Sendai virus/Parainfluenza type 1 fusion protein F (SeV/Parainfluenza virus 1, F) IgG
SENF14-M	Alpha Diagnostics	100 ug	EUR 578.4

Monoclonal Anti-Sendai virus/Parainfluenza type 3 hemagluttinin (HA) protein (SeV/Parainfluenza virus 3, H) IgG (clone 2)
SENH33-M	Alpha Diagnostics	100 ug	EUR 578.4

Mouse antibody for Parainfluenza virus type 1
1221	Virostat	100 ug	EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 1 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 1
1224	Virostat	100 ug	EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 1 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 1
1226	Virostat	100 ug	EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 1 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 1
1231	Virostat	100 ug	EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 1 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 3
1254	Virostat	100 ug	EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 3 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 3
1256	Virostat	100 ug	EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 3 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 3
1258	Virostat	100 ug	EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 3 for WB, ELISA.

Sendai virus/Parainfluenza type 1 antigens (Vero cells, inactivated, partially pure) for ELISA/Western
SEND15-N-100	Alpha Diagnostics	100 ul	EUR 416.4

Sendai virus/Parainfluenza type 3 antigens (Vero cells, inactivated, partially pure) for ELISA/Western
SEND35-N-100	Alpha Diagnostics	100 ul	EUR 416.4

Monoclonal Anti-Sendai virus/Parainfluenza type 3 hemagluttinin (HA) protein (SeV/Parainfluenza virus 3, H) IgG (clone 1)
SENH32-M	Alpha Diagnostics	100 ug	EUR 578.4

Sendai virus/Parainfluenza type 2 antigens (Vero cells, inactivated, partially pure) for ELISA/Western, Quantitative
SEND25-N-100	Alpha Diagnostics	100 ul	EUR 416.4

NATtrol Parainfluenza Virus Type 2 Stock (Qualitative) (1 mL)
NATPARA2-ST	Zeptometrix	1 mL	EUR 1281

Recombinant Influenza Parainfluenza Type-2 Protein, Untagged, E.coli-10ug
QP12960-10ug	EnQuireBio	10ug	EUR 186

Recombinant Influenza Parainfluenza Type-2 Protein, Untagged, E.coli-1mg
QP12960-1mg	EnQuireBio	1mg	EUR 2470.8

Recombinant Influenza Parainfluenza Type-2 Protein, Untagged, E.coli-50ug
QP12960-50ug	EnQuireBio	50ug	EUR 241.2

Parainfluenza 1 antibody
10-2841	Fitzgerald	1 mg	EUR 798
Description: Parainfluenza type 1 antibody

Parainfluenza 1 Antibody
abx022121-1mg	Abbexa	1 mg	EUR 1296

Parainfluenza 1 Antibody
abx023109-1ml	Abbexa	1 ml	EUR 644.4

NATtrol Parainfluenza Virus Type 1 Stock (Qualitative) (1 mL)
NATPARA1-ST	Zeptometrix	1 mL	EUR 1281

NATtrol Parainfluenza Virus Type 3 Stock (Qualitative) (1 mL)
NATPARA3-ST	Zeptometrix	1 mL	EUR 1281

NATtrol Parainfluenza Virus Type 4 Stock (Qualitative) (1 mL)
NATPARA4-ST	Zeptometrix	1 mL	EUR 1281

Recombinant Influenza Parainfluenza Type-1 Protein, Untagged, E.coli-10ug
QP12959-10ug	EnQuireBio	10ug	EUR 186

Recombinant Influenza Parainfluenza Type-1 Protein, Untagged, E.coli-1mg
QP12959-1mg	EnQuireBio	1mg	EUR 2470.8

Recombinant Influenza Parainfluenza Type-1 Protein, Untagged, E.coli-50ug
QP12959-50ug	EnQuireBio	50ug	EUR 241.2

Recombinant Influenza Parainfluenza Type-3 Protein, Untagged, E.coli-10ug
QP12961-10ug	EnQuireBio	10ug	EUR 186

Recombinant Influenza Parainfluenza Type-3 Protein, Untagged, E.coli-1mg
QP12961-1mg	EnQuireBio	1mg	EUR 2470.8

Recombinant Influenza Parainfluenza Type-3 Protein, Untagged, E.coli-50ug
QP12961-50ug	EnQuireBio	50ug	EUR 241.2

Parainfluenza 1/2/3 IgA ELISA kit
55R-IB79268	Fitzgerald	96 wells	EUR 379.2
Description: ELISA kit for the detection of Parainfluenza 1/2/3 IgA in the research laboratory

Parainfluenza 1/2/3 IgG ELISA kit
55R-IB79269	Fitzgerald	96 wells	EUR 379.2
Description: ELISA kit for the detection of Parainfluenza 1/2/3 IgG in the research laboratory

Parainfluenza 1/2/3 IgM ELISA kit
55R-IB79270	Fitzgerald	96 wells	EUR 379.2
Description: ELISA kit for the detection of Parainfluenza 1/2/3 IgM in the research laboratory

Parainfluenza 1/2/3 IgM ELISA Kit
DEIA1949	Creative Diagnostics	96T	EUR 972
Description: The Parainfluenza 1/2/3 IgG ELISA has been designed for measurement of specific IgM antibodies respectively against Parainfluenza virus type 1/2/3 in serum and plasma. Further applications in other body fluids are possible and can be provided on request.

Parainfluenza 1/2/3 IgG ELISA Kit
DEIA369	Creative Diagnostics	96T	EUR 674.4
Description: The Parainfluenza 1/2/3 IgG antibody ELISA kit has been designed for the detectionand the quantitative determination of specific IgG antibodies against Parainfluenza 1/2/3 in serum and plasma.

Parainfluenza 1/2/3 IgA ELISA Kit
DEIA370	Creative Diagnostics	96T	EUR 674.4
Description: The Parainfluenza 1/2/3 IgA antibody ELISA kit has been designed for the detection and the quantitative determination of specific IgA antibodies against Parainfluenza 1/2/3 in serum and plasma.

Parainfluenza 1/2/3 IgM ELISA Kit
DEIA371	Creative Diagnostics	96T	EUR 674.4
Description: The Parainfluenza 1/2/3 IgM antibody ELISA kit has been designed for the detection and the quantitative determination of specific IgM antibodies against Parainfluenza 1/2/3 in serum and plasma.

Parainfluenza 2, Strain GREER Protein
abx069897-1ml	Abbexa	1 ml	EUR 794.4

Human Parainfluenza Virus 2 (HPIV-2) Antibody
abx411532-01mg	Abbexa	0.1 mg	EUR 760.8

Canine Parainfluenza protein
30-1253	Fitzgerald	1 mg	EUR 548.4
Description: Purified native Canine Parainfluenza protein

Virus Parainfluenza Virus 2 (HPIV-2) Protein
abx670266-1ml	Abbexa	1 ml	EUR 710.4

Human Parainfluenza Virus 2/3 (HPIV-2/3) Antibody
abx411533-1ml	Abbexa	1 ml	EUR 610.8

Mouse antibody for Parainfluenza virus
1233	Virostat	100 ug	EUR 431.93
Description: This is Mouse monoclonal FITC conjugated antibody against Parainfluenza virus type 1 for WB, ELISA.

Mouse antibody for Parainfluenza virus
1243	Virostat	100 ug	EUR 431.93
Description: This is Mouse monoclonal FITC conjugated antibody against Parainfluenza virus type 2 for WB, ELISA.

Mouse antibody for Parainfluenza virus
1259	Virostat	100 ug	EUR 431.93
Description: This is Mouse monoclonal FITC conjugated antibody against Parainfluenza virus type 3 for WB, ELISA.

Human parainfluenza virus PCR kit
PCR-H445-48R	Bioingentech	50T	EUR 987.6

Human parainfluenza virus PCR kit
PCR-H445-96R	Bioingentech	100T	EUR 1335.6

Canine parainfluenza virus PCR kit
PCR-V112-48R	Bioingentech	50T	EUR 987.6

Canine parainfluenza virus PCR kit
PCR-V112-96R	Bioingentech	100T	EUR 1335.6

Parainfluenza 3 Strain III Protein
abx060639-1mg	Abbexa	1 mg	EUR 2080.8

Parainfluenza 1 Strain VP1 Protein
abx069896-1ml	Abbexa	1 ml	EUR 878.4

Recombinant (yeast) Parainfluenza type 1 nucelocapsid protein (C35, full length, >95%, ~60 kda)
SENN15-R-10	Alpha Diagnostics	10 ug	EUR 416.4

Mouse Anti Parainfluenza Virus 2 Monoclonal Antibody
DMABT-51480MP	Creative Diagnostics	0.1 mg	EUR 1070.4

Mouse Anti Parainfluenza Virus 2 Monoclonal Antibody
DMABT-51481MP	Creative Diagnostics	0.1 mg	EUR 1070.4

Human parainfluenza virus RT PCR kit
RTq-H445-100R	Bioingentech	100T	EUR 1573.2

Human parainfluenza virus RT PCR kit
RTq-H445-150R	Bioingentech	150T	EUR 2144.4

Human parainfluenza virus RT PCR kit
RTq-H445-50R	Bioingentech	50T	EUR 1155.6

Parainfluenza 3, Strain C243 Protein
abx069898-1ml	Abbexa	1 ml	EUR 794.4

Parainfluenza virus Antibody IgA ELISA Kit
DEIA1857	Creative Diagnostics	96T	EUR 867.6
Description: The Parainfluenza virus Antibody IgA ELISA Kit is intended for measurement of IgA class antibodies against Parainfluenza Virus IgA in human serum or plasma (citrate).

Goat polyclonal antibody for Parainfluenza
1204	Virostat	1 ml	EUR 373.2
Description: This is HRP conjugated goat polyclonal antibody against Parainfluenza type 1 for WB, ELISA.

Goat polyclonal antibody for Parainfluenza
1207	Virostat	1 ml	EUR 347.1
Description: This is Biotin conjugated goat polyclonal antibody against Parainfluenza types 2 & 3 for WB, ELISA.

Goat polyclonal antibody for Parainfluenza
1211	Virostat	1 ml	EUR 327.53
Description: This is goat polyclonal antibody against Parainfluenza type 1 for WB, ELISA.

Goat polyclonal antibody for Parainfluenza
1217	Virostat	1 ml	EUR 347.1
Description: This is Biotin conjugated goat polyclonal antibody against Parainfluenza type 1 for WB, ELISA.

Goat polyclonal antibody for Parainfluenza
1201	Virostat	1 ml	EUR 327.53
Description: This is goat polyclonal antibody against Parainfluenza types 2 & 3 for WB, ELISA.

Canine parainfluenza virus RT PCR kit
RTq-V112-100R	Bioingentech	100T	EUR 1573.2

Canine parainfluenza virus RT PCR kit
RTq-V112-150R	Bioingentech	150T	EUR 2144.4

Canine parainfluenza virus RT PCR kit
RTq-V112-50R	Bioingentech	50T	EUR 1155.6

Parainfluenza 1 Strain Sendai Protein
abx060637-1mg	Abbexa	1 mg	EUR 2030.4

Human Parainfluenza Virus (PIV) ELISA Kit
abx052868-96tests	Abbexa	96 tests	EUR 801.6

NATtrol Parainfluenza Control (6 X 0.5mL)
NATPIV-ERC	Zeptometrix	6 X 0.5mL	EUR 265

Goat Anti-Human Parainfluenza 2 & 3 Polyclonal Antibody
DPAB0162	Creative Diagnostics	1 ml	EUR 889.2

Goat Anti-Human Parainfluenza 2 & 3 Polyclonal Antibody
DPAB0134	Creative Diagnostics	1 ml	EUR 889.2

Goat Anti Parainfluenza 1 Polyclonal Antibody
DPBT-66910GP	Creative Diagnostics	1 ml	EUR 1008

Goat Anti-Sendai (Sev/Parainfluenza virus 2/3) antiserum
SEND23-S	Alpha Diagnostics	100 ul	EUR 548.4

Human Parainfluenza Virus 3 (HPIV-3) Antibody
abx411110-01mg	Abbexa	0.1 mg	EUR 526.8

Human Parainfluenza Virus 1 (HPIV-1) Antibody
abx415708-1ml	Abbexa	1 ml	EUR 727.2

Human Parainfluenza Virus 1 (HPIV-1) Antibody
abx414520-1mg	Abbexa	1 mg	EUR 994.8

Human Parainfluenza Virus 3 (HPIV-3) Antibody
abx414521-1mg	Abbexa	1 mg	EUR 994.8

Goat Anti Human Parainfluenza Virus 2/3 Polyclonal Antibody
DPBT-66911GH	Creative Diagnostics	1 ml	EUR 920.4

Brain Network Connectivity and Association with Catechol-O-Methyltransferase Gene Polymorphism in Korean Attention-Deficit Hyperactivity Disorder Children

Objective: We sought to determine if the links between and within the default mode network (DMN) and dorsal attention network (DAT) exhibited different conditions according to catechol-O-methyltransferase (COMT) gene polymorphism in relationship to attention-deficit hyperactivity disorder (ADHD) symptoms.

Methods: Fifty-seven children with ADHD and 48 healthy controls (HCs) were administered an intelligence test, the Children’s Depression Inventory, the Korean ADHD rating scale, and continuous performance test. Resting-state brain functional MRI scans were obtained, and COMT genotyping was performed to distinguish valine carriers and methionine homozygotes.

Results: Compared to controls, children with ADHD showed increased ADHD scale scores, increased visual commission errors, and increased functional connectivity (FC) within the DMN and DAT. Compared to all children with ADHD, children with the methionine homozygote and those who were valine carriers showed increased FC within the DMN and DAT and decreased FC between the DMN and DAT. FC within the DMN was also increased in HC valine carriers compared to HC children with the methionine homozygote, and in children with ADHD who were valine carriers compared to HC valine carriers.

Conclusion: We observed increased brain connectivity within the DMN and DAT and altered brain connectivity within and between the DMN and DAT associated with COMT polymorphism in children with ADHD.

Ovarian cancer predisposition beyond BRCA1 and BRCA2 genes

 Several genes associated with hereditary ovarian cancer have been discovered as a result of the work done with next generation sequencing. It is estimated that approximately 23% of ovarian carcinomas have a hereditary predisposition. The most common hereditary condition is represented by germline mutations in BRCA1 or BRCA2 genes that account for 20-25% of high grade serous ovarian cancer.

A number of other hereditary ovarian cancers are associated with different genes, with a crucial role in the DNA damage response pathway, such as the mismatch repair genes in Lynch syndrome, TP53 in Li-Fraumeni syndrome, STK11 in Peutz-Jeghers syndrome, CHEK2, RAD51, BRIP1, and PALB2. The goal of this manuscript is to summarize the published data regarding the molecular pathways involved in the pathogenesis of non-BRCA related hereditary ovarian cancer and to provide a tool that might be useful in discussing risk assessment, genetic testing, prevention strategies, as well as clinical and therapeutic implications for patients with ovarian cancer.

Transcriptome analysis of duck embryo fibroblasts for the dynamic response to duck tembusu virus infection and dual regulation of apoptosis genes

Duck Tembusu virus (DTMUV) is an emerging pathogenic flavivirus that has caused enormous economic losses in Southeast Asia. However, the pathogenic mechanism and host’s responses after DTMUV infection remain poorly understood. During this study, total mRNA sequencing (RNA-Seq) analysis was used to detect the global gene expression in DEFs at various time points after DTMUV infection.

We identified 326 genes altered significantly at all time points, and these genes were dynamically enriched in multifarious biological processes, including apoptosis, innate immune response, DNA replication, cell cycle arrest and DNA repair. Next, the results showed that apoptosis was induced and the proportion of apoptosis increased with time, and pro-apoptotic molecules caspases were activated.

The RNA-seq data analysis further revealed that most pro-apoptosis and anti-apoptosis genes were early continually responsive, and the genes involved in both intrinsic and extrinsic apoptotic pathways were initiated. Further, the considerably enriched immune-relevant pathways were involved in apoptosis process, and protein-protein interactions (PPIs) analysis showed that IL6, STAT1, TNFAIP3, CFLAR and PTGS2 may be key regulators of DEFs apoptosis. In conclusion, this study not only contributes to understanding the underlying mechanism of DEFs infection with DTMUV, but also provides new insights into targets screening for antiviral therapy.

SS-B Antigen
E61A00401	EnoGene	1mg	EUR 1230

SS-B Antigen Antibody
abx022700-2ml	Abbexa	2 ml	EUR 543.6

SS-A (Ro) Protein
abx069943-1000Units	Abbexa	1000 Units	EUR 2180.4

SS-A (Ro) Protein
abx069944-02mg	Abbexa	0.2 mg	EUR 1513.2

Human SS-A/Ro antibody(Anti-Ro)ELISA Kit
GA-E0502HM-48T	GenAsia Biotech	48T	EUR 346.8

Human SS-A/Ro antibody(Anti-Ro)ELISA Kit
GA-E0502HM-96T	GenAsia Biotech	96T	EUR 559.2

Human SS-A/Ro antibody(Anti-Ro)ELISA Kit
QY-E02678	Qayee Biotechnology	96T	EUR 433.2

Protein A Antigen
E61I01601	EnoGene	100ug	EUR 411.6

Protein A Antigen
IM124	Cygnus Technologies	1 ml	EUR 342
Description: Protein A Antigen by Cygnus Technologies is available in Europe via Gentaur.

Rat Anti-SS-A/Ro ELISA Kit
ERS0293	Abclonal	96Tests	EUR 625.2

Rat SS A/Ro antibody ELISA kit
E02S0286-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat SS A/Ro antibody ELISA kit
E02S0286-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Rat SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat SS A/Ro antibody ELISA kit
E02S0286-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Rat SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig SS A/Ro antibody ELISA kit
E07S0286-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig SS A/Ro antibody ELISA kit
E07S0286-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig SS A/Ro antibody ELISA kit
E07S0286-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog SS A/Ro antibody ELISA kit
E08S0286-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog SS A/Ro antibody ELISA kit
E08S0286-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Canine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog SS A/Ro antibody ELISA kit
E08S0286-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Canine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Anti-SS-A/Ro ELISA Kit
EGTS0293	Abclonal	96Tests	EUR 625.2

SS-A (Ro) Antibody IgG ELISA Kit
DEIA1685	Creative Diagnostics	96T	EUR 928.8
Description: Anti-SS-A is an indirect solid phase enzyme immunoassay (ELISA) for the quantitative measurement of IgG class autoantibodies against SS-A (Ro, 52 and 60 kDa) in human serum or plasma.

Mouse Anti-SS-A/Ro ELISA Kit
EMS0293	Abclonal	96Tests	EUR 625.2

Sheep Anti-SS-A/Ro ELISA Kit
ESS0293	Abclonal	96Tests	EUR 625.2

Goat SS A/Ro antibody ELISA kit
E06S0286-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat SS A/Ro antibody ELISA kit
E06S0286-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat SS A/Ro antibody ELISA kit
E06S0286-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Anti-SS-A/Ro ELISA Kit
EHS0293	Abclonal	96Tests	EUR 625.2

Rabbit Anti-SS-A/Ro ELISA Kit
ERTS0293	Abclonal	96Tests	EUR 625.2

Monkey Anti-SS-A/Ro ELISA Kit
EMKS0293	Abclonal	96Tests	EUR 625.2

Mouse SS A/Ro antibody ELISA kit
E03S0286-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse SS A/Ro antibody ELISA kit
E03S0286-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse SS A/Ro antibody ELISA kit
E03S0286-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human SS A/Ro antibody ELISA kit
E01S0286-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Human SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human SS A/Ro antibody ELISA kit
E01S0286-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Human SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human SS A/Ro antibody ELISA kit
E01S0286-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Human SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human SS- A/ Ro antibody ELISA Kit
ELA-E0290h	Lifescience Market	96 Tests	EUR 988.8

Bovine Anti-SS-A/Ro ELISA Kit
EBS0293	Abclonal	96Tests	EUR 625.2

Canine Anti-SS-A/Ro ELISA Kit
ECS0293	Abclonal	96Tests	EUR 625.2

Human SS-A/Ro antibody ELISA Kit
201-12-0486	SunredBio	96 tests	EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human SS-A/Ro antibody ELISA Kit
CN-03852H1	ChemNorm	96T	EUR 520.8

Human SS-A/Ro antibody ELISA Kit
CN-03852H2	ChemNorm	48T	EUR 340.8

Porcine Anti-SS-A/Ro ELISA Kit
EPS0293	Abclonal	96Tests	EUR 625.2

Rabbit SS A/Ro antibody ELISA kit
E04S0286-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit SS A/Ro antibody ELISA kit
E04S0286-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit SS A/Ro antibody ELISA kit
E04S0286-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Chicken Anti-SS-A/Ro ELISA Kit
ECKS0293	Abclonal	96Tests	EUR 625.2

Monkey SS A/Ro antibody ELISA kit
E09S0286-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey SS A/Ro antibody ELISA kit
E09S0286-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey SS A/Ro antibody ELISA kit
E09S0286-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human SS-A/Ro antibody ELISA Kit
YLA2239HU-48T	Shanghai YL Biotech	48T	EUR 435

Human SS-A/Ro antibody ELISA Kit
YLA2239HU-96T	Shanghai YL Biotech	96T	EUR 562.5

Anserine SS-A/Ro antibody ELISA Kit
EAS0293	Abclonal	96Tests	EUR 625.2

Recombinant Human RO-52/SS-A
7-06166	CHI Scientific	10µg	Ask for price

Recombinant Human RO-52/SS-A
7-06167	CHI Scientific	50µg	Ask for price

Recombinant Human RO-52/SS-A
7-06168	CHI Scientific	1mg	Ask for price

60 kDa SS-A / Ro ribonucleoprotein Antibody
20-abx109466	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Influenza A (H1N1) Antigen
11-553	ProSci	1 mL	EUR 645
Description: Influenza A, Influenza A (H1N1)

Influenza A (H3N2) Antigen
11-554	ProSci	1 mL	EUR 645
Description: Influenza A Antigen Strain TX, Influenza A Antigen Strain Texas

Influenza A H1N1 Antigen
abx670268-1ml	Abbexa	1 ml	EUR 627.6

Leukocyte Antigen A (HLA-A) Antibody
abx233899-100ug	Abbexa	100 ug	EUR 661.2

Leukocyte Antigen A (HLA-A) Antibody
20-abx141675	Abbexa	EUR 444.00 EUR 727.20 EUR 360.00	100 ul 200 ul 50 ul

Leukocyte Antigen A (HLA-A) Antibody
abx025201-100ul	Abbexa	100 ul	EUR 627.6

Leukocyte Antigen A (HLA-A) Antibody
20-abx001779	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Leukocyte Antigen A (HLA-A) Antibody
abx145235-100ug	Abbexa	100 ug	EUR 469.2

Inactivated HMPV A Antigen
VAng-Lsx0261-200L	Creative Biolabs	200 µL	EUR 2334
Description: Inactivated Metapneumovirus A antigen by 4mM binary ethylinimine treatment.

Protein A Antigen Concentrate
F603X	Cygnus Technologies	250 ul	EUR 308.4
Description: Protein A Antigen Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Protein A Antigen Concentrate
F613X	Cygnus Technologies	250 ul	EUR 262.8
Description: Protein A Antigen Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Protein A Antigen Concentrate
F044	Cygnus Technologies	200 ul	EUR 308.4
Description: Protein A Antigen Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Protein A Antigen Concentrate
F403H	Cygnus Technologies	200 ul	EUR 308.4
Description: Protein A Antigen Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Guinea Pig Anti-SS-A/Ro ELISA Kit
EGS0293	Abclonal	96Tests	EUR 625.2

Human Anti-SS-A (RO-52) ELISA kit
YLA4157HU-48T	Shanghai YL Biotech	48T	EUR 435

Human Anti-SS-A (RO-52) ELISA kit
YLA4157HU-96T	Shanghai YL Biotech	96T	EUR 562.5

Guinea pig SS A/Ro antibody ELISA kit
E05S0286-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig SS A/Ro antibody ELISA kit
E05S0286-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig SS A/Ro antibody ELISA kit
E05S0286-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Antigen 85-A Antibody (HRP)
20-abx109227	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

60 kDa SS-A / Ro ribonucleoprotein Antibody (HRP)
20-abx107904	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

60 kDa SS-A / Ro ribonucleoprotein Antibody (FITC)
20-abx106485	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

60 kDa SS-A / Ro ribonucleoprotein Antibody (Biotin)
20-abx105070	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Antigen 85-A Antibody (FITC)
20-abx107809	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

60 kDa SS-A/Ro ribonucleoprotein Polyclonal Antibody
42572-100ul	SAB	100ul	EUR 399.6

Antigen 85-A (Ag85A) Antibody
20-abx110661	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Human 60KDA SS-A/Ro ribonucleoprotein (TROVE2)
1-CSB-EP025071HU1	Cusabio	EUR 456.00 EUR 256.80 EUR 1570.80 EUR 672.00 EUR 1047.60 EUR 314.40	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human 60KDA SS-A/Ro ribonucleoprotein(TROVE2),partial expressed in E.coli

Antigen 85-A Antibody (Biotin)
20-abx106397	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

M. Tuberculosis 85-A Antigen
DAGA-181	Creative Diagnostics	100 µg	EUR 868.8

Influenza A Virus Antigen (H5N1)
VAng-Lsx011-1mL	Creative Biolabs	1 mL	EUR 883.2
Description: Natural antigen of Influenza A virus subtype H5N1.

Influenza A (H3N2) Antigen Protein
abx061421-1ml	Abbexa	1 ml	EUR 718.8

JSR Protein A Antigen Concentrate
F743X	Cygnus Technologies	0.3 ml	EUR 493.2
Description: JSR Protein A Antigen Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Pig Leukocyte Antigen A (HLA-A) ELISA Kit
abx361055-96tests	Abbexa	96 tests	EUR 990

Recombinant Hepatitis B Virus Core Antigen (a. a. 183)
DAG593	Creative Diagnostics	1mg	EUR 1009.2

Human Leukocyte Antigen A (HLA-A) CLIA Kit
abx197215-96tests	Abbexa	96 tests	EUR 990

Native Salmonella paratyphi A antigen
DAGA-3049	Creative Diagnostics	100ul	EUR 936

Human Leukocyte Antigen A (HLA-A) ELISA Kit
abx252628-96tests	Abbexa	96 tests	EUR 848.4

Sheep Leukocyte Antigen A (HLA-A) ELISA Kit
abx364147-96tests	Abbexa	96 tests	EUR 1111.2

Human leukocyte antigen A,HLA-A ELISA Kit
201-12-0445	SunredBio	96 tests	EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human leukocyte antigen A,HLA-A ELISA Kit
CN-04192H1	ChemNorm	96T	EUR 542.4

Human leukocyte antigen A,HLA-A ELISA Kit
CN-04192H2	ChemNorm	48T	EUR 362.4

Human leukocyte antigen A(HLA-A)ELISA Kit
GA-E0461HM-48T	GenAsia Biotech	48T	EUR 346.8

Human leukocyte antigen A(HLA-A)ELISA Kit
GA-E0461HM-96T	GenAsia Biotech	96T	EUR 559.2

Human HLA-A(Leukocyte Antigen A) ELISA Kit
EH3227	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human leukocyte antigen A(HLA-A)ELISA Kit
QY-E02401	Qayee Biotechnology	96T	EUR 433.2

Human leukocyte antigen A,HLA-A ELISA Kit
YLA1604HU-48T	Shanghai YL Biotech	48T	EUR 435

Human leukocyte antigen A,HLA-A ELISA Kit
YLA1604HU-96T	Shanghai YL Biotech	96T	EUR 562.5

Rabbit Leukocyte Antigen A (HLA-A) ELISA Kit
abx363025-96tests	Abbexa	96 tests	EUR 990

Monkey Leukocyte Antigen A (HLA-A) ELISA Kit
abx359381-96tests	Abbexa	96 tests	EUR 990

Chicken Leukocyte Antigen A (HLA-A) ELISA Kit
abx356025-96tests	Abbexa	96 tests	EUR 990