Berberine Inhibits the gene Expression and Production

lumicyte

Berberine Inhibits the gene Expression and Production of Proinflammatory Cytokines by Mononuclear cells in Rheumatoid Arthritis and Healthy Individuals

  •  Objective: Rheumatoid arthritis (RA) is the most prevalent autoimmune arthritis. Berberine is an alkaloid isolated from Berberis vulgaris and its anti-inflammatory effect has been identified.
  • Method: Twenty newly diagnosed RA patients and 20 healthy controls participated. Peripheral mononuclear cells were prepared and stimulated with bacterial lipopolysachharide (LPS,1 µg/ml), exposed to different concentrations of berberine (10 and 50µM) and dexamethasone (10-7 M) as a reference. Toxicity of compounds was evaluated by WST-1 assay. Expression of TNF-α and IL-1β were determined by quantitative real-time PCR. Protein level of secreted TNF-α and IL1β were measured by using ELISA.
  • Result: Berberine did not have any toxic effect on cells, whereas Lipopolysachharide (LPS) stimulation caused a noticeable rise in TNF-α and IL-1β production. Berberine markedly downregulated the expression of both TNF-α and IL1β and inhibits TNF-α and IL-1β secretion from LPS-stimulated PBMCs.
  • Discussion: This study provided molecular basis for anti-inflammatory effect of berberine on human mononuclear cells through the suppression of TNF-a and IL-1secretion. Our findings highlighted the significant inhibitory effect of berberine on proinflammatory responses of mononuclear cells from rheumatoid arthritis individuals, which may be responsible for antiinflammatory property of Barberry. We observed that berberine at high concentration exhibited anti-inflammatory effect in PBMCs of both healthy and patient groups by suppression of TNF-a and IL-1cytokines at both mRNA and protein levels.
  • Conclusions: Berberine may inhibit the gene expression and production of pro-inflammatory cytokines by mononuclear cells in rheumatoid arthritis and healthy individuals without affecting cells viability. Future studies with larger sample size is needed to prove the idea.

Parainfluenza Virus Type 3 Antigen

PR-BA1263-S 250µg
EUR 366.3
Description: native, Vero cell culture

OPMA04417-1ML - Parainfluenza Type 2 Antigen Protein

OPMA04417-1ML 1ml
EUR 559

OPMA04406-1ML - Parainfluenza Type 3 Antigen Protein

OPMA04406-1ML 1ml
EUR 559

Human Parainfluenza Virus Type 1 Lysate

NAT41619-100 0.1
EUR 512.85
Description: Parainfluenza Virus is an enveloped, negative-sense single-stranded RNA virus with a diameter of approximately 150 to 250 nm.

Human Parainfluenza Virus Type 3 Lysate

NAT41621-100 0.1
EUR 512.85
Description: Parainfluenza Virus is an enveloped, negative-sense single-stranded RNA virus with a diameter of approximately 150 to 250 nm.

Human Parainfluenza Virus Type 3 Lysate

NAT41621-500 0.5
EUR 2181.53
Description: Parainfluenza Virus is an enveloped, negative-sense single-stranded RNA virus with a diameter of approximately 150 to 250 nm.

Human Parainfluenza Virus Type 4A Lysate

NAT41622-100 0.1
EUR 512.85
Description: Parainfluenza Virus is an enveloped, negative-sense single-stranded RNA virus with a diameter of approximately 150 to 250 nm.

Human Parainfluenza Virus Type 4A Lysate

NAT41622-500 0.5
EUR 2181.53
Description: Parainfluenza Virus is an enveloped, negative-sense single-stranded RNA virus with a diameter of approximately 150 to 250 nm.

Parainfluenza Type-2

iha-029 10µg
EUR 60
Description: Parainfluenza Virus Type-2

OPEF01532-1ML - Parainfluenza Virus type 2 (PIV-2) Grade 2 Antigen

OPEF01532-1ML 1ml
EUR 635

Parainfluenza type 2 antibody

10-P53A 1 mg
EUR 603.6
Description: Mouse monoclonal Parainfluenza type 2 antibody

Parainfluenza type 2 antibody

10-P53B 1 mg
EUR 159.6
Description: Mouse monoclonal Parainfluenza type 2 antibody

Parainfluenza type 2 antibody

10C-CR3015M1 100 ug
EUR 250.8
Description: Mouse monoclonal Parainfluenza type 2 antibody

Parainfluenza Type 2 Antibody

abx022124-1mg 1 mg
EUR 1387.2

Parainfluenza Type 2 Antibody

abx022129-1mg 1 mg
EUR 777.6

OPEF01533-1ML - Parainfluenza Virus type 3 (PIV-3) Grade 2 Antigen

OPEF01533-1ML 1ml
EUR 635

Parainfluenza Type 2&3 Antibody

abx023113-1ml 1 ml
EUR 718.8

Parainfluenza type 2 antibody (FITC)

61C-CR3015M1F 100 ug
EUR 553.2
Description: Mouse monoclonal Parainfluenza type 2 antibody (FITC)

Parainfluenza Type-2 Protein

30-1996 50 ug
EUR 280.8
Description: Purified Parainfluenza type 2 protein

Parainfluenza type 2 protein

30-AP53 1 ml
EUR 489.6
Description: Purified Parainfluenza type 2 protein

Parainfluenza Virus, Canine Antigen

DAGA-513 1mg
EUR 1263.6

Human Parainfluenza Virus Type 3 Fusion Protein (HEK293), His-Tag

REC31965-100 0.1
EUR 2098.61
Description: Recombinant human Parainfluenza Virus Type 3 fusion protein, manufactured in HEK293 cells.

Human Parainfluenza Virus Type 3 Fusion Protein (HEK293), His-Tag

REC31965-20 0.02
EUR 432.48
Description: Recombinant human Parainfluenza Virus Type 3 fusion protein, manufactured in HEK293 cells.

Parainfluenza Type-3

iha-030 10µg
EUR 60
Description: Parainfluenza Virus Type-3

Parainfluenza Type 2&3 Antibody (HRP)

abx023112-1ml 1 ml
EUR 718.8

Parainfluenza type 1 antibody

10-P43A 1 mg
EUR 609.6
Description: Mouse monoclonal Parainfluenza type 1 antibody

Parainfluenza type 1 antibody

10-P43B 1 mg
EUR 588
Description: Mouse monoclonal Parainfluenza type 1 antibody

Parainfluenza type 1 antibody

10-P43D 1 mg
EUR 159.6
Description: Mouse monoclonal Parainfluenza type 1 antibody

Parainfluenza type 3 antibody

10-P63A 1 mg
EUR 537.6
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 3 antibody

10-P63B 1 mg
EUR 537.6
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 3 antibody

10-P63C 1 mg
EUR 418.8
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 3 antibody

10C-CR3016M1 100 ug
EUR 489.6
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 3 antibody

10C-CR3016M2 100 ug
EUR 163.2
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 3 antibody

10C-CR3016M3 100 ug
EUR 163.2
Description: Mouse monoclonal Parainfluenza type 3 antibody

Parainfluenza type 1 antibody

20-PG89 1 mg
EUR 139.2
Description: Goat polyclonal Parainfluenza type 1 antibody

Parainfluenza Type 1 Antibody

abx022123-1mg 1 mg
EUR 994.8

Parainfluenza Type 3 Antibody

abx022126-1mg 1 mg
EUR 994.8

Parainfluenza Type 3 Antibody

abx022127-1mg 1 mg
EUR 994.8

Parainfluenza Type 1 Antibody

abx022128-1mg 1 mg
EUR 777.6

Parainfluenza Type 3 Antibody

abx022130-1mg 1 mg
EUR 777.6

Parainfluenza Virus Type-2

7-07954 10µg Ask for price

Parainfluenza Virus Type-2

7-07955 50µg Ask for price

Parainfluenza Virus Type-2

7-07956 1mg Ask for price

Recombinant Canine Parainfluenza Antigen

E41H060 100ug
EUR 395

Parainfluenza type 1 + 3 antibody

10-P43C 1 mg
EUR 523.2
Description: Mouse monoclonal Parainfluenza type 1 + 3 antibody

Parainfluenza Type 1&3 Antibody

abx022122-1mg 1 mg
EUR 994.8

Parainfluenza type 3 antibody (FITC)

61C-CR3016M2F 100 ug
EUR 553.2
Description: Mouse monoclonal Parainfluenza type 3 antibody (FITC)

OAMA00238-1MG - Parainfluenza Type 2 Antibody

OAMA00238-1MG 1mg
EUR 1149

OAMA02035-1MG - Parainfluenza Type 2 Antibody

OAMA02035-1MG 1mg
EUR 1149

Parainfluenza Type-1 protein

30-1995 50 ug
EUR 295.2
Description: Purified Parainfluenza type 1 protein

Parainfluenza Type-3 Protein

30-1997 50 ug
EUR 295.2
Description: Purified Parainfluenza type 3 protein

Parainfluenza type 1 protein

30-AP43 1 ml
EUR 508.8
Description: Purified Parainfluenza type 1 protein

Parainfluenza type 3 protein

30-AP63 1 ml
EUR 489.6
Description: Purified Parainfluenza type 3 protein

OOSA09770-1ML - NATIVE PARAINFLUENZA VIRUS 2 Antigen

OOSA09770-1ML 1ml
EUR 519

Canine Parainfluenza Virus Antigen Test Card

C11521 15T Ask for price

Parainfluenza Virus Type-2 Protein

20-abx260514
  • EUR 276.00
  • EUR 3082.80
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Parainfluenza Virus Type-1

7-07951 10µg Ask for price

Parainfluenza Virus Type-1

7-07952 50µg Ask for price

Parainfluenza Virus Type-1

7-07953 1mg Ask for price

Parainfluenza Virus Type-3

7-07957 10µg Ask for price

Parainfluenza Virus Type-3

7-07958 50µg Ask for price

Parainfluenza Virus Type-3

7-07959 1mg Ask for price

Monoclonal Anti-Sendai virus/Parainfluenza type 3 (SeV/Parainfluenza virus 3) IgG

SEND31-M 100 ug
EUR 578.4

OPPA01557-10UG - Parainfluenza Type-2 Protein

OPPA01557-10UG 10ug
EUR 70

OAMA00248-1MG - Parainfluenza Type 3 Antibody

OAMA00248-1MG 1mg
EUR 799

OAMA00273-1MG - Parainfluenza Type 3 Antibody

OAMA00273-1MG 1mg
EUR 799

OAMA00276-1MG - Parainfluenza Type 1 Antibody

OAMA00276-1MG 1mg
EUR 849

OAMA00322-1MG - Parainfluenza Type 1 Antibody

OAMA00322-1MG 1mg
EUR 749

OAMA02034-1MG - Parainfluenza Type 1 Antibody

OAMA02034-1MG 1mg
EUR 649

OAMA02036-1MG - Parainfluenza Type 3 Antibody

OAMA02036-1MG 1mg
EUR 649

Mouse antibody for Parainfluenza virus type 2

1241 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 2 for WB, ELISA.

OPEF01505-1MG - Canine Parainfluenza Virus (CPIV) Antigen

OPEF01505-1MG 1mg
EUR 628

Parainfluenza Virus Type-1 Protein

20-abx260513
  • EUR 276.00
  • EUR 3082.80
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Parainfluenza Virus Type-3 Protein

20-abx260515
  • EUR 276.00
  • EUR 3082.80
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Monoclonal Anti-Sendai virus/Parainfluenza type 1 fusion protein F (SeV/Parainfluenza virus 1, F) IgG

SENF14-M 100 ug
EUR 578.4

OPPA01556-10UG - Parainfluenza Type-1 Protein

OPPA01556-10UG 10ug
EUR 70

OPPA01558-10UG - Parainfluenza Type-3 Protein

OPPA01558-10UG 10ug
EUR 70

Monoclonal Anti-Sendai virus/Parainfluenza type 3 hemagluttinin (HA) protein (SeV/Parainfluenza virus 3, H) IgG (clone 2)

SENH33-M 100 ug
EUR 578.4

Sendai virus/Parainfluenza type 1 antigens (Vero cells, inactivated, partially pure) for ELISA/Western

SEND15-N-100 100 ul
EUR 416.4

Sendai virus/Parainfluenza type 3 antigens (Vero cells, inactivated, partially pure) for ELISA/Western

SEND35-N-100 100 ul
EUR 416.4

Mouse antibody for Parainfluenza virus type 1

1221 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 1 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 1

1224 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 1 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 1

1226 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 1 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 1

1231 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 1 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 3

1254 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 3 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 3

1256 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 3 for WB, ELISA.

Mouse antibody for Parainfluenza virus type 3

1258 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Parainfluenza virus type 3 for WB, ELISA.

OAEF00298-1MG - Parainfluenza Virus type 2 (PIV-2) Antibody

OAEF00298-1MG 1mg
EUR 471

Monoclonal Anti-Sendai virus/Parainfluenza type 3 hemagluttinin (HA) protein (SeV/Parainfluenza virus 3, H) IgG (clone 1)

SENH32-M 100 ug
EUR 578.4

Sendai virus/Parainfluenza type 2 antigens (Vero cells, inactivated, partially pure) for ELISA/Western, Quantitative

SEND25-N-100 100 ul
EUR 416.4

Parainfluenza Virus 2 (+ Type 3) goat polyclonal antibody, HRP

BP1053HRP 1 ml Ask for price

NATtrol Parainfluenza Virus Type 2 Stock (Qualitative) (1 mL)

NATPARA2-ST 1 mL
EUR 1281

Recombinant Influenza Parainfluenza Type-2 Protein, Untagged, E.coli-10ug

QP12960-10ug 10ug
EUR 186

Recombinant Influenza Parainfluenza Type-2 Protein, Untagged, E.coli-1mg

QP12960-1mg 1mg
EUR 2470.8

Recombinant Influenza Parainfluenza Type-2 Protein, Untagged, E.coli-50ug

QP12960-50ug 50ug
EUR 241.2

Parainfluenza Virus 2 (+ Type 3) goat polyclonal antibody, Ig Fraction

BP1053 1 ml Ask for price

OAEF00260-1MG - Parainfluenza Virus type 3 (PIV-3) Antibody

OAEF00260-1MG 1mg
EUR 471

OAEF00261-1MG - Parainfluenza Virus type 3 (PIV-3) Antibody

OAEF00261-1MG 1mg
EUR 471

OAEF00262-1MG - Parainfluenza Virus type 3 (PIV-3) Antibody

OAEF00262-1MG 1mg
EUR 471

OAEF00296-1MG - Parainfluenza Virus type 1 (PIV-1) Antibody

OAEF00296-1MG 1mg
EUR 471

OAEF00297-1MG - Parainfluenza Virus type 1 (PIV-1) Antibody

OAEF00297-1MG 1mg
EUR 471

Human Parainfluenza virus type 2 antibody IgG(PIV2-IgG) ELISA Kit定性

SL2983Hu 96 Tests
EUR 468

Human Parainfluenza virus type 2 antibody IgM(PIV2-IgM) ELISA Kit定性

SL2984Hu 96 Tests
EUR 468

ViPrimePLUS Human Parainfluenza Virus type 2 RT-qPCR Kit, 150rxns

QM5044 each Ask for price

Parainfluenza 1 antibody

10-2841 1 mg
EUR 798
Description: Parainfluenza type 1 antibody

Parainfluenza 1 Antibody

abx022121-1mg 1 mg
EUR 1296

Parainfluenza 1 Antibody

abx023109-1ml 1 ml
EUR 644.4

NATtrol Parainfluenza Virus Type 1 Stock (Qualitative) (1 mL)

NATPARA1-ST 1 mL
EUR 1281

NATtrol Parainfluenza Virus Type 3 Stock (Qualitative) (1 mL)

NATPARA3-ST 1 mL
EUR 1281

NATtrol Parainfluenza Virus Type 4 Stock (Qualitative) (1 mL)

NATPARA4-ST 1 mL
EUR 1281

Recombinant Influenza Parainfluenza Type-1 Protein, Untagged, E.coli-10ug

QP12959-10ug 10ug
EUR 186

Recombinant Influenza Parainfluenza Type-1 Protein, Untagged, E.coli-1mg

QP12959-1mg 1mg
EUR 2470.8

Recombinant Influenza Parainfluenza Type-1 Protein, Untagged, E.coli-50ug

QP12959-50ug 50ug
EUR 241.2

Recombinant Influenza Parainfluenza Type-3 Protein, Untagged, E.coli-10ug

QP12961-10ug 10ug
EUR 186

Recombinant Influenza Parainfluenza Type-3 Protein, Untagged, E.coli-1mg

QP12961-1mg 1mg
EUR 2470.8

Recombinant Influenza Parainfluenza Type-3 Protein, Untagged, E.coli-50ug

QP12961-50ug 50ug
EUR 241.2

Human Parainfluenza virus type 1 antibody IgG(PIV1-IgG) ELISA Kit定性

SL2981Hu 96 Tests
EUR 468

Human Parainfluenza virus type 1 antibody IgM(PIV1-IgM) ELISA Kit定性

SL2982Hu 96 Tests
EUR 468

Human Parainfluenza virus type 3 antibody IgG(PIV3-IgG) ELISA Kit定性

SL2985Hu 96 Tests
EUR 468

Brain Network Connectivity and Association with Catechol-O-Methyltransferase Gene Polymorphism in Korean Attention-Deficit Hyperactivity Disorder Children

Objective: We sought to determine if the links between and within the default mode network (DMN) and dorsal attention network (DAT) exhibited different conditions according to catechol-O-methyltransferase (COMT) gene polymorphism in relationship to attention-deficit hyperactivity disorder (ADHD) symptoms.

Methods: Fifty-seven children with ADHD and 48 healthy controls (HCs) were administered an intelligence test, the Children’s Depression Inventory, the Korean ADHD rating scale, and continuous performance test. Resting-state brain functional MRI scans were obtained, and COMT genotyping was performed to distinguish valine carriers and methionine homozygotes.

Results: Compared to controls, children with ADHD showed increased ADHD scale scores, increased visual commission errors, and increased functional connectivity (FC) within the DMN and DAT. Compared to all children with ADHD, children with the methionine homozygote and those who were valine carriers showed increased FC within the DMN and DAT and decreased FC between the DMN and DAT. FC within the DMN was also increased in HC valine carriers compared to HC children with the methionine homozygote, and in children with ADHD who were valine carriers compared to HC valine carriers.

Conclusion: We observed increased brain connectivity within the DMN and DAT and altered brain connectivity within and between the DMN and DAT associated with COMT polymorphism in children with ADHD.

Ovarian cancer predisposition beyond BRCA1 and BRCA2 genes

 Several genes associated with hereditary ovarian cancer have been discovered as a result of the work done with next generation sequencing. It is estimated that approximately 23% of ovarian carcinomas have a hereditary predisposition. The most common hereditary condition is represented by germline mutations in BRCA1 or BRCA2 genes that account for 20-25% of high grade serous ovarian cancer.

A number of other hereditary ovarian cancers are associated with different genes, with a crucial role in the DNA damage response pathway, such as the mismatch repair genes in Lynch syndrome, TP53 in Li-Fraumeni syndrome, STK11 in Peutz-Jeghers syndrome, CHEK2, RAD51, BRIP1, and PALB2. The goal of this manuscript is to summarize the published data regarding the molecular pathways involved in the pathogenesis of non-BRCA related hereditary ovarian cancer and to provide a tool that might be useful in discussing risk assessment, genetic testing, prevention strategies, as well as clinical and therapeutic implications for patients with ovarian cancer.

Transcriptome analysis of duck embryo fibroblasts for the dynamic response to duck tembusu virus infection and dual regulation of apoptosis genes

Duck Tembusu virus (DTMUV) is an emerging pathogenic flavivirus that has caused enormous economic losses in Southeast Asia. However, the pathogenic mechanism and host’s responses after DTMUV infection remain poorly understood. During this study, total mRNA sequencing (RNA-Seq) analysis was used to detect the global gene expression in DEFs at various time points after DTMUV infection.

We identified 326 genes altered significantly at all time points, and these genes were dynamically enriched in multifarious biological processes, including apoptosis, innate immune response, DNA replication, cell cycle arrest and DNA repair. Next, the results showed that apoptosis was induced and the proportion of apoptosis increased with time, and pro-apoptotic molecules caspases were activated.

The RNA-seq data analysis further revealed that most pro-apoptosis and anti-apoptosis genes were early continually responsive, and the genes involved in both intrinsic and extrinsic apoptotic pathways were initiated. Further, the considerably enriched immune-relevant pathways were involved in apoptosis process, and protein-protein interactions (PPIs) analysis showed that IL6, STAT1, TNFAIP3, CFLAR and PTGS2 may be key regulators of DEFs apoptosis. In conclusion, this study not only contributes to understanding the underlying mechanism of DEFs infection with DTMUV, but also provides new insights into targets screening for antiviral therapy.

SS-A Antigen

E61A00301 1mg
EUR 1230

Borrelia Afzelii Antigen

NAT41583-100 0.1
EUR 391.66
Description: Harvested bacteria are washed and detergent solubilized to produce a cytoplasmic extract enriched with lipoproteins and outer surface proteins (OSPs). The antigen is presented in phosphate buffered saline containing 1 % n-octyl-β-D-glucopyranoside.

Borrelia Afzelii Antigen

NAT41583-500 0.5
EUR 1176.24
Description: Harvested bacteria are washed and detergent solubilized to produce a cytoplasmic extract enriched with lipoproteins and outer surface proteins (OSPs). The antigen is presented in phosphate buffered saline containing 1 % n-octyl-β-D-glucopyranoside.

Borrelia Garinii Antigen

NAT41584-100 0.1
EUR 391.66
Description: Harvested bacteria are washed and detergent solubilized to produce a cytoplasmic extract enriched with lipoproteins and outer surface proteins (OSPs). The antigen is presented in phosphate buffered saline containing 1 % n-octyl-β-D-glucopyranoside.

Borrelia Garinii Antigen

NAT41584-500 0.5
EUR 1176.24
Description: Harvested bacteria are washed and detergent solubilized to produce a cytoplasmic extract enriched with lipoproteins and outer surface proteins (OSPs). The antigen is presented in phosphate buffered saline containing 1 % n-octyl-β-D-glucopyranoside.

Brucella Abortus Antigen

NAT41599-100 0.1
EUR 391.66
Description: Brucella abortus lysate, produced by fermentation.

Brucella Abortus Antigen

NAT41599-500 0.5
EUR 1176.24
Description: Brucella abortus lysate, produced by fermentation.

Candida Albicans Antigen

NAT41601-100 0.1
EUR 391.66
Description: Candida albicans is grown on solid medium, washed, disrupted and subjected to an extraction process. The antigen consists of cytoplasmic and cell wall components.

Candida Albicans Antigen

NAT41601-500 0.5
EUR 1176.24
Description: Candida albicans is grown on solid medium, washed, disrupted and subjected to an extraction process. The antigen consists of cytoplasmic and cell wall components.

Canine Parvovirus Antigen

NAT41594-100 0.1
EUR 391.66
Description: Canine Parvovirus, produced in CRFK cells.

Canine Coronavirus Antigen

NAT41590-100 0.1
EUR 391.66
Description: Canine Coronavirus produced in A-72 cells.

Feline Calicivirus Antigen

NAT41595-100 0.1
EUR 391.66
Description: Feline Calicivirus produced in FC 3TG cells.

Helicobacter Pylori Antigen

NAT41603-100 0.1
EUR 391.66
Description: Bacteria are cultured on solid medium, harvested, washed and solubilised. The antigen is partially purified by detergent extraction and centrifugation.

Helicobacter Pylori Antigen

NAT41603-500 0.5
EUR 1176.24
Description: Bacteria are cultured on solid medium, harvested, washed and solubilised. The antigen is partially purified by detergent extraction and centrifugation.

Campylobacter Jejuni Antigen

NAT41600-100 0.1
EUR 391.66
Description: Campylobacter jejuni is cultured on solid medium. This antigen is a partially purified detergent extract of the membrane fraction. The main component is an outer membrane protein, approximately 45 kDa in SDS-PAGE.

Campylobacter Jejuni Antigen

NAT41600-500 0.5
EUR 1176.24
Description: Campylobacter jejuni is cultured on solid medium. This antigen is a partially purified detergent extract of the membrane fraction. The main component is an outer membrane protein, approximately 45 kDa in SDS-PAGE.

Mycoplasma Pneumoniae Antigen

MP901-1000 1.0
EUR 1010.39
Description: Mycoplasma pneumoniae whole organisms that have been purified and detergent treated to enrich antigenic proteins and decrease background.

Mycoplasma Pneumoniae Antigen

MP901-200 0.2
EUR 270.46
Description: Mycoplasma pneumoniae whole organisms that have been purified and detergent treated to enrich antigenic proteins and decrease background.

Chlamydia Trachomatis Antigen

CT022-1000 1.0
EUR 378.9
Description: Chlamydia trachomatis antigens from clarified cell lysate.

Neisseria Gonorrhoeae Antigen

NG01-1000 1.0
EUR 378.9
Description: Homogenised lysate of pure bacteria.

Echovirus Antigen, Recombinant

REC31776-100 0.1
EUR 276.84
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus

Echovirus Antigen, Recombinant

REC31776-500 0.5
EUR 1043.56
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus

Trichomonas Vaginalis Antigen

TV01-1000 1.0
EUR 421
Description: Washed & lysed suspension of whole protozoa

Echinococcus Granulosus Antigen

NAT41602-100 0.1
EUR 391.66
Description: Echinococcus granulosus material is derived from bovine hydatid cyst as sterile filtered cyst fluid.

Echinococcus Granulosus Antigen

NAT41602-500 0.5
EUR 1176.24
Description: Echinococcus granulosus material is derived from bovine hydatid cyst as sterile filtered cyst fluid.

Enterovirus Antigen, Recombinant

REC31772-100 0.1
EUR 276.84
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus IgA, IgG and IgM ELISA.

Enterovirus Antigen, Recombinant

REC31772-500 0.5
EUR 1043.56
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus IgA, IgG and IgM ELISA.

Cytomegalovirus Purified Antigen

CMV-HP-100 0.1
EUR 318.94
Description: A concentrated source of human Cytomegalovirus particles purified by sucrose gradient ultracentrifugation.

Cytomegalovirus Purified Antigen

CMV-HP-1000 1.0
EUR 2096.06
Description: A concentrated source of human Cytomegalovirus particles purified by sucrose gradient ultracentrifugation.

Cytomegalovirus Purified Antigen

CMV-HP-500 0.5
EUR 1279.58
Description: A concentrated source of human Cytomegalovirus particles purified by sucrose gradient ultracentrifugation.

Astrovirus Antigen (Type 1)

AS02-1000 1.0
EUR 1654.65
Description: A concentrated source of Astrovirus particles and Astrovirus proteins from a lysate of host cells.

Astrovirus Antigen (Type 1)

AS02-200 0.2
EUR 442.69
Description: A concentrated source of Astrovirus particles and Astrovirus proteins from a lysate of host cells.

Yersinia pestis V antigen

REC32028-100 0.1
EUR 491.53
Description: Yersinia pestis V antigen (LcrV antigen, capsule protein fraction 1, type III secretion system needle tip protein). The protein is produced as an N-terminal GST fusion, with GST being cleaved by thrombin and is not present in the final product.

Yersinia pestis V antigen

REC32028-500 0.5
EUR 2421.37
Description: Yersinia pestis V antigen (LcrV antigen, capsule protein fraction 1, type III secretion system needle tip protein). The protein is produced as an N-terminal GST fusion, with GST being cleaved by thrombin and is not present in the final product.

Canine Herpes Virus Antigen

NAT41592-100 0.1
EUR 391.66
Description: Canine Herpes virus, produced in MDCK cells.

Canine Adenovirus 1 Antigen

NAT41587-100 0.1
EUR 391.66
Description: Canine Adenovirus Type 1, produced in A-72 cells.

Canine Adenovirus 2 Antigen

NAT41588-100 0.1
EUR 391.66
Description: Canine Adenovirus Type 2, produced in A-72 cells.

Canine Distemper Virus Antigen

NAT41591-100 0.1
EUR 391.66
Description: Canine Distemper virus, produced in SL-29 cells.

Norovirus GII.4 VP1 Antigen

REC31620-100 0.1
EUR 302.36
Description: Recombinant Norovirus GII.4 VP1 antigen produced in 293 human cells.

Norovirus GII.4 VP1 Antigen

REC31620-1000 1.0
EUR 1830.71
Description: Recombinant Norovirus GII.4 VP1 antigen produced in 293 human cells.

Norovirus GII.4 VP1 Antigen

REC31620-500 0.5
EUR 1066.53
Description: Recombinant Norovirus GII.4 VP1 antigen produced in 293 human cells.

Canine Parainfluenza Virus Antigen

NAT41593-100 0.1
EUR 391.66
Description: Canine Parainfluenza virus antigen, produced in MDCK cells.

Feline Panleukopenia Virus Antigen

NAT41597-100 0.1
EUR 391.66
Description: Feline Panleukopenia Virus (FPLV; feline parvovirus) antigen, produced in CRFK cells.

Cytomegalovirus Cell Lysate Antigen

CMV-CL-100 0.1
EUR 223.26
Description: A clarified cell lysate containing a mix of CMV antigens from all stages of the replication life cycle.

Cytomegalovirus Cell Lysate Antigen

CMV-CL-1000 1.0
EUR 1422.47
Description: A clarified cell lysate containing a mix of CMV antigens from all stages of the replication life cycle.

Feline Viral Rhinotracheitis Antigen

NAT41598-100 0.1
EUR 391.66
Description: Feline Viral Rhinotracheitis (FVR; feline herpes virus, FHV-1) antigen, produced in CRFK cells.

Herpes Simplex Virus 1 Antigen

HS105-1000 1.0
EUR 1178.79
Description: HSV-1 particles from a cell lysate are purified by sucrose gradient ultracentrifugation.

Herpes Simplex Virus 1 Antigen

HS105-200 0.2
EUR 294.7
Description: HSV-1 particles from a cell lysate are purified by sucrose gradient ultracentrifugation.

Herpes Simplex Virus 2 Antigen

HS205-1000 1.0
EUR 1178.79
Description: HSV-2 particles from a cell lysate are purified by sucrose gradient ultracentrifugation.

Herpes Simplex Virus 2 Antigen

HS205-200 0.2
EUR 294.7
Description: HSV-2 particles from a cell lysate are purified by sucrose gradient ultracentrifugation.

Ross River Virus Recombinant Antigen

REC31969-100 0.1
EUR 757.8
Description: Recombinant Ross River virus antigen expressed in HEK293 cells as virus-like particles and purified by sucrose density gradients and precipitation. Virus-like particles were then solubilized in PBS containing 0.2% SDS to prevent aggregation of particles. The preparation is not particulate. Antigens in the preparation include Envelope proteins 1 and 2 and Nucleoprotein.

Ross River Virus Recombinant Antigen

REC31969-500 0.5
EUR 2844.92
Description: Recombinant Ross River virus antigen expressed in HEK293 cells as virus-like particles and purified by sucrose density gradients and precipitation. Virus-like particles were then solubilized in PBS containing 0.2% SDS to prevent aggregation of particles. The preparation is not particulate. Antigens in the preparation include Envelope proteins 1 and 2 and Nucleoprotein.

Canine Adenovirus 1 and 2 Antigen

NAT41589-100 0.1
EUR 391.66
Description: A mixture of Canine Adenovirus Type 1 and Type 2, produced in A-72 cells.

Hepatitis B Virus E Antigen (HBeAg)

REC31677-100 0.1
EUR 456.72
Description: Recombinant Hepititis B Virus E Protein (HBeAg).

Hepatitis B Virus E Antigen (HBeAg)

REC31677-500 0.5
EUR 1941.06
Description: Recombinant Hepititis B Virus E Protein (HBeAg).

Hepatitis B Virus Core Antigen (HBcAg)

REC31689-100 0.1
EUR 456.72
Description: Recombinant Hepititis B Virus Core Protein (HBcAg).

Hepatitis B Virus Core Antigen (HBcAg)

REC31689-500 0.5
EUR 1370.16
Description: Recombinant Hepititis B Virus Core Protein (HBcAg).

Hepatitis C Virus Core Antigen (HCcAg)

REC31693-100 0.1
EUR 484.79
Description: Recombinant Hepatitis C Virus core protein is produced in E. coli and fused with a His-tag.

Hepatitis C Virus Core Antigen (HCcAg)

REC31693-500 0.5
EUR 1455.64
Description: Recombinant Hepatitis C Virus core protein is produced in E. coli and fused with a His-tag.

Herpes Simplex Virus 1 Lysate Antigen

HS104-1000 1.0
EUR 270.46
Description: A high concentration of HSV-1 particles and proteins from a clarified cell lysate.

Herpes Simplex Virus 2 Lysate Antigen

HS204-1000 1.0
EUR 270.46
Description: A high concentration of HSV-2 particles and proteins from a clarified cell lysate.

Feline Infectious Peritonitis Virus Antigen

NAT41596-100 0.1
EUR 391.66
Description: Feline Infectious Peritonitis virus (FIPV; feline coronavirus) antigen, produced in CRFK cells.

Legionella pneumophila antigen (native extract)

NAT41580-100 0.1
EUR 391.66
Description: Inactivated Legionella pneumophila antigen from culture.

Streptococcus Pneumoniae Antigen, Native Extract

NAT41604-100 0.1
EUR 391.66
Description: Inactivated Streptococcus pneumoniae antigen from culture.

Leptospira Biflexa Antigen (Strain Patoc 1)

NAT41582-100 0.1
EUR 391.66
Description: Inactivated Leptospira biflexa antigen (Strain Patoc 1) from broth culture.

Leptospira Biflexa Antigen (Strain Patoc 1)

NAT41582-500 0.5
EUR 1176.24
Description: Inactivated Leptospira biflexa antigen (Strain Patoc 1) from broth culture.

OPEF01636-1MG - Recombinant SS-A Antigen

OPEF01636-1MG 1mg
EUR 1683

Mouse Anti-Hepatitis B Surface Antigen Antibody (1834)

MAB12230-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus surface antigen (1834).

Mouse Anti-Hepatitis B Surface Antigen Antibody (1837)

MAB12231-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus surface antigen (1837)

Mouse Anti-Hepatitis B Surface Antigen Antibody (1838)

MAB12232-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus surface antigen (1838)

SS-B Antigen

E61A00401 1mg
EUR 1230

Mouse Anti-Hepatitis B Virus E Antigen Antibody (1892)

MAB12226-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (1892)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (1893)

MAB12227-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (1893)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (1894)

MAB12228-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (1894)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (M132)

MAB12298-100 0.1
EUR 276.84
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (M132)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (M132)

MAB12298-500 0.5
EUR 695.29
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (M132)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (M133)

MAB12299-100 0.1
EUR 276.84
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (M133)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (M133)

MAB12299-500 0.5
EUR 695.29
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (M133)

Yersinia pestis chain B F1 capsule antigen, C-terminal His-tag

REC32027-100 0.1
EUR 491.53
Description: Yersinia pestis chain B F1 capsule antigen (Antig_Caf1)

Yersinia pestis chain B F1 capsule antigen, C-terminal His-tag

REC32027-500 0.5
EUR 2421.37
Description: Yersinia pestis chain B F1 capsule antigen (Antig_Caf1)

SS-B Antigen Antibody

abx022700-2ml 2 ml
EUR 543.6

SS-A (Ro) Protein

abx069943-1000Units 1000 Units
EUR 2180.4

SS-A (Ro) Protein

abx069944-02mg 0.2 mg
EUR 1513.2

OPEF01637-1MG - Recombinant SS-B Antigen

OPEF01637-1MG 1mg
EUR 1683

Human SS-A/Ro antibody(Anti-Ro)ELISA Kit

GA-E0502HM-48T 48T
EUR 346.8

Human SS-A/Ro antibody(Anti-Ro)ELISA Kit

GA-E0502HM-96T 96T
EUR 559.2

Human SS-A/Ro antibody(Anti-Ro)ELISA Kit

QY-E02678 96T
EUR 433.2

OPMA04220-200UG - SS-B (La) Antigen Protein

OPMA04220-200UG 0.2MG
EUR 1199

OPMA00020-100UG - SS-B (La) Antigen, Recombinant

OPMA00020-100UG 0.1MG
EUR 549

Rat Anti-SS-A/Ro ELISA Kit

ERS0293 96Tests
EUR 625.2

Rat SS A/Ro antibody ELISA kit

E02S0286-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat SS A/Ro antibody ELISA kit

E02S0286-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat SS A/Ro antibody ELISA kit

E02S0286-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig SS A/Ro antibody ELISA kit

E07S0286-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig SS A/Ro antibody ELISA kit

E07S0286-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig SS A/Ro antibody ELISA kit

E07S0286-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog SS A/Ro antibody ELISA kit

E08S0286-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog SS A/Ro antibody ELISA kit

E08S0286-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog SS A/Ro antibody ELISA kit

E08S0286-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine SS A/Ro antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Anti-SS-A/Ro ELISA Kit

EGTS0293 96Tests
EUR 625.2

Rat SS A/Ro antibody ELISA kit

E01A16589 96T
EUR 700
Description: ELISA

Protein A Antigen

E61I01601 100ug
EUR 411.6

Protein A Antigen

IM124 1 ml
EUR 342
Description: Protein A Antigen by Cygnus Technologies is available in Europe via Gentaur.

SS-A (Ro) Antibody IgG ELISA Kit

DEIA1685 96T
EUR 928.8
Description: Anti-SS-A is an indirect solid phase enzyme immunoassay (ELISA) for the quantitative measurement of IgG class autoantibodies against SS-A (Ro, 52 and 60 kDa) in human serum or plasma.

Mouse Anti-SS-A/Ro ELISA Kit

EMS0293 96Tests
EUR 625.2

Sheep Anti-SS-A/Ro ELISA Kit

ESS0293 96Tests
EUR 625.2

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