Oxidative Stress and Analysis of Selected SNPs

lumicyte

Oxidative Stress and Analysis of Selected SNPs of ACHE (rs 2571598), BCHE (rs 3495), CAT (rs 7943316), SIRT1 (rs 10823108), GSTP1 (rs 1695), and Gene GSTM1GSTT1 in Chronic Organophosphates Exposed Groups from Cameroon and Pakistan

The detrimental effects of organophosphates (OPs) on human health are thought to be of systemic, i.e., irreversible inhibition of acetylcholinesterase (AChE) at nerve synapses. However, several studies have shown that AChE inhibition alone cannot explain all the toxicological manifestations in prolonged exposure to OPs.

The present study aimed to assess the status of antioxidants malondialdehyde (MDA), superoxide dismutase (SOD), glutathione (GSH) (reduced), catalase, and ferric reducing antioxidant power (FRAP) in chronic OP-exposed groups from Cameroon and Pakistan. Molecular analysis of genetic polymorphisms (SNPs) of glutathione transferases (GSTM1, GSTP1, GSTT1), catalase gene (CAT, rs7943316), sirtuin 1 gene (SIRT1, rs10823108), acetylcholinesterase gene (ACHE, rs2571598), and butyrylcholinesterase gene (BCHE, rs3495) were screened in the OP-exposed individuals to find the possible causative association with oxidative stress and toxicity.

Cholinesterase and antioxidant activities were measured by colorimetric methods using a spectrophotometer. Salting-out method was employed for DNA extraction from blood followed by restriction fragment length polymorphism (RFLP) for molecular analysis. Cholinergic enzymes were significantly decreased in OP-exposed groups. Catalase and SOD were decreased and MDA and FRAP were increased in OP-exposed groups compared to unexposed groups in both groups. GSH was decreased only in Pakistani OPs-exposed group. Molecular analysis of ACHE, BCHE, Catalase, GSTP1, and GSTM1 SNPs revealed a tentative association with their phenotypic expression that is level of antioxidant and cholinergic enzymes.

The study concludes that chronic OPs exposure induces oxidative stress which is associated with the related SNP polymorphism. The toxicogenetics of understudied SNPs were examined for the first time to our understanding. The findings may lead to a newer area of investigation on OPs induced health issues and toxicogenetics.

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Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

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Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

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EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

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EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

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EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker) (LLC/1738), CF488A conjugate, 0.1mg/mL

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EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker) (LLC/1738), CF488A conjugate, 0.1mg/mL

BNC881738-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker) (N10/2), CF640R conjugate, 0.1mg/mL

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EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker) (N10/2), CF640R conjugate, 0.1mg/mL

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EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker) (LLC/1738), CF640R conjugate, 0.1mg/mL

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EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker) (LLC/1738), CF640R conjugate, 0.1mg/mL

BNC401738-500 500uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker)(rLLC/1738), CF647 conjugate, 0.1mg/mL

BNC473773-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker)(rLLC/1738), CF647 conjugate, 0.1mg/mL

BNC473773-500 1uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker)(rLLC/3777), CF647 conjugate, 0.1mg/mL

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EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker)(rLLC/3777), CF647 conjugate, 0.1mg/mL

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EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker)(LLC/3778R), CF647 conjugate, 0.1mg/mL

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Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

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EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker)(rLLC/1738), CF568 conjugate, 0.1mg/mL

BNC683773-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker)(rLLC/1738), CF568 conjugate, 0.1mg/mL

BNC683773-500 1uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker)(rLLC/3777), CF568 conjugate, 0.1mg/mL

BNC683777-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker)(rLLC/3777), CF568 conjugate, 0.1mg/mL

BNC683777-500 1uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Lambda Light Chain (B-Cell Marker)(LLC/3778R), CF568 conjugate, 0.1mg/mL

BNC683778-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Is CHEK2 a moderate-risk breast cancer gene or the younger sister of Li-Fraumeni?

 The CHEK2 gene is mostly considered as a moderate breast cancer gene with the result that many clinicians have a narrow focus. We present the 10-year journey of a man who had five different cancers and had iterative genetic testing including for Li-Fraumeni syndrome, eventually to discover a pathogenic variant in the CHEK2 gene, possibly explaining his numerous cancers. This diagnosis offered him closure which he had desperately sought for well over a decade.

A pathogenic variant in the CHEK2 gene can potentially explain these cancers because of its function as a tumour suppressor gene. Consideration is warranted of what this means for individuals with CHEK2 variants who may develop multiple cancers, their prognosis and whether different treatment modalities such as chemotherapy, radiotherapy or target agents would need modification. We encourage more research into the many faces of the CHEK2 gene and the potential for predisposition to multiple cancers.

Functional classification of prostate cancer‑associated miRNAs through CRISPR/Cas9‑mediated gene knockout

 The aim of the present study was to use the clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR‑associated (Cas) 9‑mediated gene knockout technology for the rapid classification of the differential function of micro (mi)RNAs screened using miRNA expression profiling by microarray.

The rational design of single guide RNAs for the CRISPR/Cas9 system was verified to function in human LNCaP cells with rapid and efficient target gene editing. miRNA (miR)‑205, miR‑221, miR‑222, miR‑30c, miR‑224, miR‑455‑3p, miR‑23b and miR‑505 were downregulated in patients with prostate cancer (PCa) and were experimentally validated to function as tumor suppressors in prostate cancer cells, affecting tumor proliferation, invasion and aerobic glycolysis. In addition, the data of the present study suggested that miR‑663a and mfiR‑1225‑5p were upregulated in prostate cancer tissues and cell proliferation of miR‑663a and miR‑1225‑5p knockout PCa cells was significantly lower compared with miR‑NC cells. Furthermore, knockout of miR‑1225‑5p and miR‑663a significantly decreased the lactate production in LNCaP cells in vitro. In conclusion, the present study offered a simple and efficient method for rapidly classifying miRNA function by applying CRISPR/Cas9 in LNCaP cells.

The present study suggested, for the first time to the best of the authors’ knowledge, that the aberrant expression of miR‑663a and miR‑1225‑5p may be involved with the progression of prostate cancer, implying their potential as candidate markers for this type of cancer. However, the precise role of miR‑663a and miR‑1225‑5p in accelerating the development of prostate cancer and promoting tumor progression remains to be elucidated.

BAI1 Antibody

37437-100ul 100ul
EUR 302.4

BAI1 Antibody

E037437 100μg/100μl
EUR 255
Description: Available in various conjugation types.

BAI1 Antibody

E11-213G 100μg
EUR 225
Description: Available in various conjugation types.

BAI1 Antibody

E19-4911 100μg/100μl
EUR 225
Description: Available in various conjugation types.

BAI1 Antibody

DF4911 200ul
EUR 420

BAI1 Antibody

DF4911-100ul 100ul
EUR 280

BAI1 Antibody

DF4911-200ul 200ul
EUR 350

BAI1 Antibody

E38PA4579 100ul
EUR 225
Description: Available in various conjugation types.

BAI1 antibody

70R-31424 100 ug
EUR 294
Description: Rabbit polyclonal BAI1 antibody

BAI1 Antibody

1-CSB-PA013118
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  • 100ul
  • 50ul
Description: A polyclonal antibody against BAI1. Recognizes BAI1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

BAI1 Antibody

1-CSB-PA040081
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  • 100ug
  • 50ug
Description: A polyclonal antibody against BAI1. Recognizes BAI1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/10000

BAI1 Antibody

1-CSB-PA080282
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  • 100ug
  • 50ug
Description: A polyclonal antibody against BAI1. Recognizes BAI1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB;WB:1:500-1:2000

BAI1 Antibody

1-CSB-PA172172
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  • 100ul
  • 50ul
Description: A polyclonal antibody against BAI1. Recognizes BAI1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

BAI1 Polyclonal Antibody

ABP57293-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of BAI1 from Human, Mouse, Rat. This BAI1 antibody is for WB. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

BAI1 Polyclonal Antibody

ABP57293-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of BAI1 from Human, Mouse, Rat. This BAI1 antibody is for WB. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

BAI1 Polyclonal Antibody

ABP57293-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of BAI1 from Human, Mouse, Rat. This BAI1 antibody is for WB. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

BAI1 Polyclonal Antibody

E910346 100ul
EUR 225
Description: Available in various conjugation types.

BAI1 Polyclonal Antibody

E20-53488 100ug
EUR 225
Description: Available in various conjugation types.

BAI1 Conjugated Antibody

C37437 100ul
EUR 476.4

BAI1 Polyclonal Antibody

E44H11111 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

BAI1 Antibody (N-term)

GWB-81A9D4 0.05 mg Ask for price

OAAF04857-100UG - BAI1 Antibody

OAAF04857-100UG 100ug
EUR 329

OAAF06142-100UG - BAI1 Antibody

OAAF06142-100UG 100ug
EUR 329

Rabbit Polyclonal BAI1 Antibody

TA309583 100 µl Ask for price

Rabbit Anti Human Bai1 (N-Terminal) Polyclonal Antibody

CPBT-66603RH 50 µg
EUR 1182

BAI1 Rabbit Polyclonal Antibody

E12-463 100μg/100μl
EUR 255
Description: Available in various conjugation types.

BAI1 Rabbit Polyclonal Antibody

EA261-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against BAI1 from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

BAI1 Rabbit Polyclonal Antibody

EA261-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against BAI1 from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

BAI1 Rabbit Polyclonal Antibody

ES8290-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against BAI1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC

BAI1 Rabbit Polyclonal Antibody

ES8290-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against BAI1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC

Polyclonal BAI1 (extracellular) Antibody

APR00510G 0.05ml
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BAI1 (extracellular) . This antibody is tested and proven to work in the following applications:

Anti- Brain-Specific Angiogenesis Inhibitor 1 (BAI1) Human Antibody

GWB-8F5989 0.05 mg Ask for price

BAI1 Rabbit Polyclonal Antibody(A181)

RA20204-100ul 100 ul
EUR 298

BAI1 Rabbit Polyclonal Antibody(A181)

RA20204-50ul 50 ul
EUR 198

Polyclonal ADGRB1 / BAI1 Antibody (C-Terminus)

APR01949G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ADGRB1 / BAI1 (C-Terminus). This antibody is tested and proven to work in the following applications:

Polyclonal ADGRB1 / BAI1 Antibody (C-Terminus)

APR01950G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ADGRB1 / BAI1 (C-Terminus). This antibody is tested and proven to work in the following applications:

Polyclonal ADGRB1 / BAI1 Antibody (N-Terminus)

APR02051G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ADGRB1 / BAI1 (N-Terminus). This antibody is tested and proven to work in the following applications:

BAI1-Associated Protein 3 (BAIAP3) Antibody

abx230795-100ug 100 ug
EUR 610.8

BAI1-Associated Protein 3 (BAIAP3) Antibody

20-abx334255
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

BAI1-Associated Protein 3 (BAIAP3) Antibody

abx230795-100g 100 µg
EUR 350

BAI1-Associated Protein 3 (BAIAP3) Antibody

abx334255-100g 100 µg
EUR 362.5

BAI1-Associated Protein 3 (BAIAP3) Antibody

abx334255-20g 20 µg
EUR 162.5

BAI1-Associated Protein 3 (BAIAP3) Antibody

abx334255-50g 50 µg
EUR 250

Human BAI1 shRNA Plasmid

20-abx950393
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  • 150 µg
  • 300 µg

BAI1 (untagged)-Human brain-specific angiogenesis inhibitor 1 (BAI1)

SC303054 10 µg Ask for price

OAAB17561-400UL - BAI1 Antibody - C-terminal region

OAAB17561-400UL 400ul
EUR 389

BAI1-Associated Protein 3 (BAIAP3) Antibody (HRP)

20-abx334791
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

BAI1-Associated Protein 3 (BAIAP3) Antibody (HRP)

abx334791-100g 100 µg
EUR 362.5

BAI1-Associated Protein 3 (BAIAP3) Antibody (HRP)

abx334791-20g 20 µg
EUR 162.5

BAI1-Associated Protein 3 (BAIAP3) Antibody (HRP)

abx334791-50g 50 µg
EUR 250

Brain Specific Angiogenesis Inhibitor 1 (BAI1) Antibody

20-abx121991
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  • 100 ul
  • 200 ul
  • 30 ul

Brain Specific Angiogenesis Inhibitor 1 (BAI1) Antibody

20-abx133924
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  • 100 ul
  • 200 ul
  • 30 ul

Brain Specific Angiogenesis Inhibitor 1 (BAI1) Antibody

20-abx015270
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Brain Specific Angiogenesis Inhibitor 1 (BAI1) Antibody

20-abx171468
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  • 1 mg
  • 200 ug

Brain Specific Angiogenesis Inhibitor 1 (BAI1) Antibody

20-abx175624
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Brain Specific Angiogenesis Inhibitor 1 (BAI1) Antibody

20-abx321241
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  • 100 ul
  • 50 ul

BAI1-Associated Protein 3 (BAIAP3) Antibody (FITC)

20-abx334792
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

BAI1-Associated Protein 3 (BAIAP3) Antibody (FITC)

abx334792-100g 100 µg
EUR 362.5

BAI1-Associated Protein 3 (BAIAP3) Antibody (FITC)

abx334792-20g 20 µg
EUR 162.5

BAI1-Associated Protein 3 (BAIAP3) Antibody (FITC)

abx334792-50g 50 µg
EUR 250

BAI1 (GFP-tagged) - Human brain-specific angiogenesis inhibitor 1 (BAI1)

RG224196 10 µg Ask for price

BAI1-Associated Protein 3 (BAIAP3) Antibody (Biotin)

20-abx334793
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

BAI1-Associated Protein 3 (BAIAP3) Antibody (Biotin)

abx334793-100g 100 µg
EUR 362.5

BAI1-Associated Protein 3 (BAIAP3) Antibody (Biotin)

abx334793-20g 20 µg
EUR 162.5

BAI1-Associated Protein 3 (BAIAP3) Antibody (Biotin)

abx334793-50g 50 µg
EUR 250

Human BAI1 knockout cell line

ABC-KH1322 1 vial Ask for price
Description: Human BAI1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

BAI1-associated protein 1 (BAIAP1) polyclonal antibody

ABP-PAB-10426 100 ug Ask for price

BAI1-associated protein 2 (BAIAP2) polyclonal antibody

ABP-PAB-10427 100 ug Ask for price

BAI1-associated protein 3 (BAIAP3) polyclonal antibody

ABP-PAB-10428 100 ug Ask for price

BAI1

574581 10.0mg
EUR 270

BAI1

HY-103269 5mg
EUR 198

BAI1

T5210-10mg 10mg Ask for price
Description: BAI1

BAI1

T5210-1g 1g Ask for price
Description: BAI1

BAI1

T5210-1mg 1mg Ask for price
Description: BAI1

BAI1

T5210-50mg 50mg Ask for price
Description: BAI1

BAI1

T5210-5mg 5mg Ask for price
Description: BAI1

Human BAI1 knockdown cell line

ABC-KD1322 1 vial Ask for price
Description: Human BAI1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

BAI1 ORF Vector (Human) (pORF)

ORF016093 1.0 ug DNA
EUR 790.8

BAI1 (Myc-DDK-tagged)-Human brain-specific angiogenesis inhibitor 1 (BAI1)

RC224196 10 µg Ask for price

BAI1 ELISA Kit (Human) (OKCD01663)

OKCD01663 96 Wells
EUR 997.2
Description: Description of target: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 13.1 pg/mL

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx122473-100ug 100 ug
EUR 469.2

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

20-abx133925
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  • 100 ul
  • 200 ul
  • 30 ul

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

20-abx014278
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx027435-400ul 400 ul
EUR 627.6

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx027435-80l 80 µl
EUR 343.2

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

20-abx325942
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  • 100 ug
  • 50 ug

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx331739-100ul 100 ul
EUR 510

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx014278-100g 100 µg
EUR 43.75

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx122473-100l 100 µl Ask for price

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx122473-20l 20 µl
EUR 337.5

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx122473-50l 50 µl Ask for price

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx027435-400l 400 µl
EUR 518.75

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx325942-100g 100 µg
EUR 250

BAI1 Associated Protein 2 Like 2 (BAIAP2L2) Antibody

abx325942-50g 50 µg
EUR 187.5

BAI1 (ADGRB1) rabbit polyclonal antibody, Aff - Purified

AP01307PU-N 100 µg Ask for price

Brain-specific angiogenesis inhibitor 1 Antibody / BAI1

F54968-0.08ML 0.08 ml
EUR 140.25
Description: Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.

Brain-specific angiogenesis inhibitor 1 Antibody / BAI1

F54968-0.4ML 0.4 ml
EUR 322.15
Description: Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.

OKCD01663-96W - BAI1 ELISA Kit (Human)

OKCD01663-96W 96Wells
EUR 675

BAI1 siRNA

20-abx908855
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  • 15 nmol
  • 30 nmol

BAI1 siRNA

20-abx908856
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  • Ask for price
  • 15 nmol
  • 30 nmol

BAI1 sgRNA CRISPR Lentivector set (Human)

K0167901 3 x 1.0 ug
EUR 406.8

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx171468-1ml 1 ml
EUR 787.5

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx175624-1096tests 10 × 96 tests
EUR 750

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx175624-596tests 5 × 96 tests
EUR 337.5

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx175624-96tests 96 tests
EUR 275

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx015270-1mg 1 mg
EUR 43.75

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx212954-100l 100 µl
EUR 350

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx212954-50l 50 µl
EUR 250

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx212955-100l 100 µl
EUR 350

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx212955-50l 50 µl
EUR 250

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx326074-100g 100 µg
EUR 250

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx326074-50g 50 µg
EUR 187.5

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx321241-100g 100 µg
EUR 350

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx321241-50g 50 µg
EUR 250

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx329761-100g 100 µg Ask for price

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx329761-20g 20 µg
EUR 187.5

Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody

abx329761-50g 50 µg
EUR 250

BAI1 inhibitor

565686 1.0g
EUR 3450

Brain Specific Angiogenesis Inhibitor 1 (BAI1) Polyclonal Antibody

CAU31554-100ul 100ul
EUR 235.2

Brain Specific Angiogenesis Inhibitor 1 (BAI1) Polyclonal Antibody

CAU31554-200ul 200ul
EUR 294

Brain-specific angiogenesis inhibitor 1 (BAI1) polyclonal antibody

ABP-PAB-10421 100 ug Ask for price

BAI1-Associated Protein 2 Human (Recombinant)

22061144-1 2 µg
EUR 137.27

BAI1-Associated Protein 2 Human Recombinant

rAP-3771 Inquiry Ask for price

BAI1 (ADGRB1) (N-term) rabbit polyclonal antibody, Aff - Purified

AP06996PU-N 50 µg Ask for price

BAI1 Protein Vector (Human) (pPM-C-HA)

PV064371 500 ng
EUR 2955.6

BAI1 Protein Vector (Human) (pPB-C-His)

PV064369 500 ng
EUR 2955.6

BAI1 Protein Vector (Human) (pPB-N-His)

PV064370 500 ng
EUR 2955.6

BAI1 Protein Vector (Human) (pPM-C-His)

PV064372 500 ng
EUR 2955.6

Human BAI1 associated protein 3(BAIAP3) ELISA kit

E01A1796 96T
EUR 700
Description: ELISA

Human BAI1 associated protein 3(BAIAP3) ELISA kit

E01B0743-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human BAI1 associated protein 3(BAIAP3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human BAI1 associated protein 3(BAIAP3) ELISA kit

E01B0743-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human BAI1 associated protein 3(BAIAP3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human BAI1 associated protein 3(BAIAP3) ELISA kit

E01B0743-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human BAI1 associated protein 3(BAIAP3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human BAI1- associated protein 3, BAIAP3 ELISA KIT

ELI-50000h 96 Tests
EUR 988.8

BAI1 Protein Vector (Human) (pPB-His-MBP)

PV326182 500 ng
EUR 2955.6

BAI1 Protein Vector (Human) (pPB-His-GST)

PV326183 500 ng
EUR 2955.6

Human BAI1-Associated Protein 3 (BAIAP3) ELISA Kit

20-abx386003
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

BAI1-associated Protein 3 (BAIAP3) Rabbit anti-Human Polyclonal (aa1171-1187) Antibody

GWB-2F6222 0.05 mg Ask for price

BAI1 sgRNA CRISPR Lentivector (Human) (Target 1)

K0167902 1.0 ug DNA
EUR 184.8

BAI1 sgRNA CRISPR Lentivector (Human) (Target 2)

K0167903 1.0 ug DNA
EUR 184.8

BAI1 sgRNA CRISPR Lentivector (Human) (Target 3)

K0167904 1.0 ug DNA
EUR 184.8

Brain-Specific Angiogenesis Inhibitor 1 (BAI1) Rabbit anti-Human Polyclonal Antibody

GWB-81D4E3 0.05 mg Ask for price

Rabbit Polyclonal antibody to BAIAP2L1 (BAI1-associated protein 2-like 1)

TA308115 100 µl Ask for price

BAI1-Associated 2

PR27243 5 ug
EUR 229.2

BAI1-Associated 2

PR27243-B each
EUR 184.5

BAI1 Blocking Peptide

20-abx161790
  • Ask for price
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  • 1 mg
  • 5 mg

BAI1 Blocking Peptide

DF4911-BP 1mg
EUR 234

Bai1 (untagged) - Rat brain-specific angiogenesis inhibitor 1 (Bai1)

RN217658 10 µg Ask for price

BAIAP2 BAI1-Associated Protein 2 Human Recombinant Protein

PROTQ9UQB8 Regular: 20ug
EUR 380.4
Description: BAIAP2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 530 amino acids (1-522) and having a molecular mass of 58.4kDa.;BAIAP2 is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

BAIAP2L2 (untagged)-Human BAI1-associated protein 2-like 2 (BAIAP2L2)

SC122979 10 µg Ask for price

BAIAP2L2 (untagged)-Human BAI1-associated protein 2-like 2 (BAIAP2L2)

SC317898 10 µg Ask for price

BAIAP2L1 (untagged)-Human BAI1-associated protein 2-like 1 (BAIAP2L1)

SC321226 10 µg Ask for price

BAI1 Protein Vector (Human) (pPM-N-D-C-HA)

PV326184 500 ng
EUR 2955.6

BAI1 Protein Vector (Human) (pPM-N-D-C-His)

PV326185 500 ng
EUR 2955.6

Bai1 (untagged) - Mouse brain-specific angiogenesis inhibitor 1 (Bai1), (10ug)

MC224714 10 µg Ask for price

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) Protein

20-abx652708
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human BAI1(Brain Specific Angiogenesis Inhibitor 1) ELISA Kit

ELK4950-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BAI1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human BAI1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human BAI1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human BAI1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human BAI1(Brain Specific Angiogenesis Inhibitor 1) ELISA Kit

ELK4950-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BAI1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human BAI1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human BAI1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human BAI1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse BAI1 shRNA Plasmid

20-abx979845
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  • 150 µg
  • 300 µg

BAIAP2L1 (GFP-tagged) - Human BAI1-associated protein 2-like 1 (BAIAP2L1)

RG202617 10 µg Ask for price

Bai1 (myc-DDK-tagged) - Rat brain-specific angiogenesis inhibitor 1 (Bai1)

RR217658 10 µg Ask for price

Bai1 (Myc-DDK-tagged) - Mouse brain-specific angiogenesis inhibitor 1 (Bai1)

MR215473 10 µg Ask for price

Bai1 (GFP-tagged) - Mouse brain-specific angiogenesis inhibitor 1 (Bai1), (10ug)

MG215473 10 µg Ask for price

BAIAP3 (untagged)-Human BAI1-associated protein 3 (BAIAP3), transcript variant 1

SC303402 10 µg Ask for price

BAIAP2 (untagged)-Human BAI1-associated protein 2 (BAIAP2), transcript variant 2

SC310273 10 µg Ask for price

BAIAP2 (untagged)-Human BAI1-associated protein 2 (BAIAP2), transcript variant 3

SC110153 10 µg Ask for price

BAIAP2 (untagged)-Human BAI1-associated protein 2 (BAIAP2), transcript variant 1

SC110154 10 µg Ask for price

BAIAP3 (untagged) - Human BAI1-associated protein 3 (BAIAP3), transcript variant 6

SC337912 10 µg Ask for price

BAIAP2 (untagged)-Human BAI1-associated protein 2 (BAIAP2), transcript variant 4

SC326039 10 µg Ask for price

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) CLIA Kit

20-abx493631
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

20-abx150784
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

DLR-BAI1-Hu 96T
EUR 475
Description: serum, plasma, tissue homogenates or other biological fluids.

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

DLR-BAI1-Hu-48T 48T
EUR 632.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

DLR-BAI1-Hu-96T 96T
EUR 825.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

EKN43909-48T 48T
EUR 378.7

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

EKN43909-5x96T 5x96T
EUR 2569.75

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

EKN43909-96T 96T
EUR 541

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

EKL55770-5x96T 5x96T
EUR 3888.83

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

EKL55770-96T 96T
EUR 818.7

Human Brain- specific angiogenesis inhibitor 1, BAI1 ELISA KIT

ELI-34745h 96 Tests
EUR 988.8

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

EKU02798-48T 48T
EUR 555.66

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

EKU02798-5x96T 5x96T
EUR 3770.55

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

EKU02798-96T 96T
EUR 793.8

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

DL-BAI1-Hu 96T
EUR 453
Description: serum, plasma, tissue homogenates or other biological fluids.

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

EK12817 96Т
EUR 768

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

RD-BAI1-Hu-48T 48T
EUR 464.3
Description: serum, plasma, tissue homogenates and other biological fluids.

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

RD-BAI1-Hu-48Tests 48 Tests
EUR 639.6

Human Brain Specific Angiogenesis Inhibitor 1 (BAI1) ELISA Kit

RD-BAI1-Hu-96T 96T
EUR 663.3
Description: serum, plasma, tissue homogenates and other biological fluids.

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